Results 91 to 100 of about 536,508 (263)

Mechanical-magnetic-electric coupled behaviors for stress-driven Terfenol-D energy harvester

open access: yesAIP Advances, 2017
The stress-driven Terfernol-D energy harvester exhibits the nonlinear mechanical-magnetic-electric coupled (MMEC) behaviors and the eddy current effects.
Shuying Cao   +7 more
doaj   +1 more source

Local Well-Posedness of a Model for Stress-Driven Growth in the Presence of Nutrients

open access: yes
A model for morphoelastic growth, that is, growth influenced by elastic stress, driven by the absorption of nutrients is considered. The model features a multiplicative decomposition of the deformation gradient into an elastic contribution and a growth tensor.
Abels, Helmut   +2 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Extracellular-matrix mediated stresses spatially bias myoblast fusion and myotube growth

open access: yesNature Communications
Myoblast fusion into multinucleated myotubes is essential for skeletal muscle development and repair, yet how tissue-scale mechanics contributes to this process remains poorly understood.
Yoann Le Toquin   +8 more
doaj   +1 more source

Investigation of Thermal Deformation Behavior in Boron Nitride-Reinforced Magnesium Alloy Using Constitutive and Machine Learning Models

open access: yesNanomaterials
Accurate flow stress prediction is vital for optimizing the manufacturing of lightweight materials under high-temperature conditions. In this study, a boron nitride (BN)-reinforced AZ80 magnesium composite was subjected to hot compression tests at ...
Ayoub Elajjani   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The role of tetramethylpyrazine and paeoniflorin in modulating iron metabolism and ferroptosis: innovative strategies for atherosclerosis treatment

open access: yesFrontiers in Pharmacology
IntroductionAtherosclerosis (AS) is driven by lipid accumulation, inflammation, and oxidative stress, leading to endothelial dysfunction and plaque formation.
Miao Zhang   +8 more
doaj   +1 more source

A Discrete Fracture Network Model with Stress-Driven Nucleation and Growth

open access: yes, 2017
The realism of Discrete Fracture Network (DFN) models, beyond the bulk statistical properties, relies on the spatial organization of fractures, which is not issued by classical stochastic DFN models. This can be improved by injecting prior information in DFN from a better knowledge of the geological fracturing processes.
Lavoine, Etienne   +3 more
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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