Results 91 to 100 of about 4,438,120 (290)

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Stressors, Appraisal of Stressors, Experienced Stress and Cardiac Response:A Real-Time, Real-Life Investigation of Work Stress in Nurses [PDF]

, 2015
Background: Stress in health care professionals may reflect both the work and appraisal of work and impacts on the individuals, their patients, colleagues and managers.Purpose: The purpose of the present study is to examine physiological and ...
Farquharson, B., Julia Allan, Marie Johnston, Martyn Jones (720171), Bell, Cheryl, Jones, Martyn C, Martyn Jones, Ian Ricketts (16669965), Marie Johnston (18271), Farquharson, Barbara, Derek Johnston, Johnston, D., Barbara Farquharson (16669962), Derek Johnston (3064002), Bell, C., Jones, M., Patricia Schofield, Jones, Martyn, Barbara Farquharson, Ricketts, I., Schofield, Patricia, Patricia Schofield (625809), Johnston, M., Cheryl Bell (16669959), Bell, Cheryl Louise, Cheryl Bell, Ian Ricketts, Johnston, Derek, Julia Allan (4991684), Allan, J., Allan, Julia, Johnston, Marie, Johnston, Derek W, Ricketts, Ian, Allan, Julia L   +34 more
core   +1 more source

Mechanical Characteristics of Solidified Chromium Contaminated Soil on the Basis of Resistivity Representations

Taiyuan Ligong Daxue xuebao
Purposes This study is conducted to explore the indirect measurement method of mechanical properties of solidified heavy metal contaminated soil. Methods The combined resistivity-unconfined compression test method was carried out to investigate the ...
MA Qianwei, ZHANG Jieya, CAO Jiawei, DONG Xiaoqiang   +3 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Stress-strain model for laterally confined concrete

, 2005
[Abstract]: High strength concrete HSC with highly desirable structural properties can lead to significant cost savings in heavily loaded lower story columns of concrete structures.
Lokuge, Weena P., Sanjayan, J. G., Setunge, Sujeeva   +2 more
core   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

An experimental method to measure dynamic stress-strain relationship of materials at high strain rates

, 2014
In this paper, an experimental method for measuring dynamic behavior of materials at high strain rates is developed. The strain and stress of a specimen are obtained using a high-precision photonic Doppler velocimetry system and a sensitive ...
Huang, CG (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Mech Fluid Solid Coupling Syst, Beijing 100190, Peoples R China., 王曦, 黄晨光, 宋宏伟, 魏延鹏, 吴先前   +5 more
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Job strain and health-related lifestyle: findings from an individual-participant meta-analysis of 118,000 working adults.

, 2013
We examined the associations of job strain, an indicator of work-related stress, with overall unhealthy and healthy lifestyles.Journal ArticleMeta-AnalysisResearch Support, Non-U.S.
Batty, G.D., Westerlund, Hugo,, Westerlund, H.,, Nyberg, Solja T, Clays, E., Ladwig, K. -H,, Clays, E.,, Nordin, Maria,, Nordin, M.,, Virtanen, M., Steptoe, A., Nyberg, S.T., Kittel, F., Marmot, Michael, Zins, M.,, Dragano, Nico, Lunau, T., Knutsson, Anders,, Erbel, R., Koskenvuo, Markku, Ferrie, Jane, Westerholm, Peter,, Oksanen, T.,, Clays, Els, Heikkilä, K.,, Ferrie, J. E.,, Oksanen, Tuula, Westerlund, Hugo, Pentti, J., Dragano, N., Casini, A.,, Batty, G. D.,, Kittel, France, Theorell, Töres, Virtanen, Marianna, Knutsson, Anders, Salo, Paula, Ladwig, K.-H., Fransson, E.I., Nordin, Maria, Marmot, M.G., De Bacquer, Dirk, Casini, Annalisa, Goldberg, M., Vahtera, J.,, Marmot, Michael G., Suominen, S.,, Casini, A., DeBacquer, Dirk, Batty, George David, Vahtera, Jussi, Nyberg, Solja T., Ladwig, Karl-Heinz, Westerholm, P.,, Fransson, E. I.,, Steptoe, A.,, Jöckel, K.-H., Fransson, Eleonor,, Fransson, Eleonor I, Fransson, Eleonor I,, Pentti, Jaana, Marmot, M. G.,, Singh-Manoux, A., IPD-Work Consortium, Erbel, R.,, Ferrie, Jane E, Pentti, J.,, Fransson, Eleonor I., Nyberg, Solja,, Westerholm, Peter, Knutsson, A., Marmot, Michael G, Heikkilä, Katriina, Batty, David, Heikkilä, Katriina,, Alfredsson, L.,, Vahtera, J., Koskenvuo, M.,, Batty, G David, Alfredsson, Lars, Ferrie, J.E., Nordin, M., Singh-Manoux, A.,, Zins, Marie, Ferrie, Jane E., Alfredsson, L., Singh-Manoux, Archana, Salo, P.,, Suominen, S., Dragano, N.,, Goldberg, Marcel, Kivimäki, Mika, Erbel, Raimund, Goldberg, M.,, Kivimaki, M., Kittel, F.,, Lunau, T.,, Jöckel, K. -H,, Westerlund, H., Oksanen, T., Nyberg, S. T.,, Suominen, Sakari, Westerholm, P.J., Kivimäki, M.,, Lunau, Thorsten, Heikkilä, K., Koskenvuo, M., DeBacquer, D.,, Steptoe, Andrew, Salo, P., Virtanen, M.,, Jöckel, Karl-Heinz, Batty, G. David, Zins, M., Debacquer, D., Suominen, S, Steptoe, A, Virtanen, M,, Fransson, EI, Heikkila, K, Nyberg, ST, Heikkilä, K;Fransson, EI;Nyberg, ST;Zins, M;Westerlund, H;Westerholm, P;Virtanen, M;Vahtera, J;Suominen, S;Steptoe, A;Salo, P;Pentti, J;Oksanen, T;Nordin, M;Marmot, MG;Lunau, T;Ladwig, KH;Koskenvuo, M;Knutsson, A;Kittel, F;Jöckel, KH;Goldberg, M;Erbel, R;Dragano, N;Debacquer, D;Clays, E;Casini, A;Alfredsson, L;Ferrie, JE;Singh-Manoux, A;Batty, GD;Kivimaki, M, Westerholm, P, Vahtera, J,, Zins, M, Westerlund, H,   +125 more
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source