Results 71 to 80 of about 289,087 (265)

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Stress-strain behavior of square concrete columns confined with hybrid B-CSM composites and development of novel prediction models

Composites Part C: Open Access
This paper presents a comprehensive investigation into the behavior of concrete confined with hybrid Basalt and Chopped Strand Mat (B-CSM) fibers. The newly proposed B-CSM confinement technique substantially enhances the brittle compressive stress-strain
Phromphat Thansirichaisree, Hisham Mohamad, Ali Ejaz, Panumas Saingam, Qudeer Hussain, Suniti Suparp   +5 more
doaj   +1 more source

Effect of Initial Backfill Temperature on the Deformation Behavior of Early Age Cemented Paste Backfill That Contains Sodium Silicate

Advances in Materials Science and Engineering, 2016
Enhancing the knowledge on the deformation behavior of cemented paste backfill (CPB) in terms of stress-strain relations and modulus of elasticity is significant for economic and safety reasons.
Aixiang Wu, Yong Wang, Bo Zhou, Jiahua Shen   +3 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Stress-Strain Behavior of Crushed Concrete as a Special Anthropogenic Soil. [PDF]

Materials (Basel), 2023
Gabryś K, Dołżyk-Szypcio K, Szypcio Z, Sas W.   +3 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Ratcheting Behavior of Intervertebral Discs Under Cyclic Compression: Experiment and Prediction

Orthopaedic Surgery, 2019
Objective To evaluate the ratcheting behavior of intervertebral discs (IVD) by experiments and theoretical study. Method The lumbar spines of sheep were obtained at a local slaughterhouse, and the IVD was processed with upper and lower vertebral bodies ...
Chun‐qiu Zhang, Tao Zhang, Lilan Gao, Cheng‐fei Du, Qing Liu, Hai‐ying Liu, Xin Wang   +6 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source