Results 31 to 40 of about 457,599 (266)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
InfrastructuresThis article presents the fundamentals of an analytical method for determining the stress–strain state of a railway subgrade reinforced with geosynthetic material.
Ahmad Alkhdour +3 more
doaj +1 more source
Stress-strain state of bending reinforced beams with cracks
Инженерно-строительный журнал, 2020 The work is dealing with studying the stress-strain state of bending pre-stressed concrete beams with cracks. The problems of determining preliminary stresses in a reinforced concrete element, determining the moment of crack formation, and determining ...
Omirkhan Khabidolda +5 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Characterization of Stress State of Corrugated Steel Web Girders Based on Mann-Kendall Criterion
Zhongwai GongluTo reasonably characterize the stress state of corrugated steel web girders and determine the failure load, the stress state evolution pattern of corrugated steel web girders was investigated in this paper based on the structural stress state theory ...
DOU Fei, CHEN Feng
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Stress-strain state of the precast monolithic bent element
Инженерно-строительный журнал, 2020 The features of the stress-strain state of a precast monolithic bent element (beam) arising as a result of its phased installation and loading are considered and experimentally investigated.
Alexandr Koyankin, Valery Mitasov
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Early Warning Model of Pipeline Stress State Based on Axial Stress Monitoring Data
Shiyou jixie, 2018 To manage the stress state of the pipeline in real time and take timely targeted measures, stress monitoring measures are usually taken for pipelines that are prone to displacement deformation.
Liu Yuqing +3 more
doaj
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source