Results 111 to 120 of about 38,947 (304)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The acquisition of English L2 prosody by Italian native speakers: experimental data and pedagogical implications [PDF]

open access: yes, 2015
This paper investigates Yes-No question intonation patterns in English L2, Italian L1, and English L1. The aim is to test the hypothesis that L2 learners may show different acquisition strategies for different dimensions of intonation, and particularly ...
Busa', Maria Grazia, Stella, A.
core  

Stressful times!

open access: yes, 2010
Within the last two years, the global economic crisis has prompted unprecedented change, with organizations traditionally considered as “solid”, crumbling and liquidating in front of incredulous stock brokers and global audiences (some examples include Fannie Mae, Freddie Mac and the Lehman Brother s Holding Inc.).
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Is It About Speech or About Prediction? Testing Between Two Accounts of the Rhythm–Reading Link

open access: yesBrain Sciences
Background/Objectives: The mechanisms underlying the positive association between reading and rhythmic skills remain unclear. Our goal was to systematically test between two major explanations: the Temporal Sampling Framework (TSF), which highlights the ...
Susana Silva   +6 more
doaj   +1 more source

Cross-linguistic and cross-scriptal differences in auditory and visual attentional shifts : a comparison between native Mandarin and English speakers [PDF]

open access: yes, 2012
Lallier (2010) proposed that our attentional shifting speed could be shaped by our native language. In our current study we tested this hypothesis by comparing the attentional shift of native English and native Mandarin speakers using the stream ...
Lee, Tsz-chung, 李子聰
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Don'cha know? A survey of ESL teachers' perspectives on reduced forms instruction [PDF]

open access: yes, 2002
The perceptual saliency of spoken English is often reduced creating variation in the way English is spoken in very formal contexts from more naturally occurring English.
Rosa, Moana
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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