Results 151 to 160 of about 37,313 (281)
Ageing Population and Balance Under Stressful Conditions-A Cross-Sectional Observational Study. [PDF]
Healthcare (Basel)Rodríguez-Costa I +6 more
europepmc +1 more source
A Dynamic Approach to Rhythm in Language: Toward a Temporal Phonology
, 1995 It is proposed that the theory of dynamical systems offers appropriate tools to model many phonological aspects of both speech production and perception.
Cummins, Fred +2 more
core +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Vowel Reduction In The English Of Educated Edo (nigerian) English Speakers
The Journal of Studies in Language, Culture and SocietyEducated Edo English (EEE) is a sub-group of Nigerian English (NigE), one of the new Englishes. Phonological studies on NigE rhythm have been on the major ethnic (Hausa, Igbo, Yoruba) and a few minority group (Isoko, Urhobo, Eka, Ibibio) while studies ...
Julianah Ajoke Akindele
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Acute stress impairs decision-making at varying levels of decision complexity. [PDF]
Commun PsycholDoroc K, Yadav N, Murawski C.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source