Results 91 to 100 of about 5,060,804 (319)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The impact of assessing simulated bad news consultations on medical students' stress response and communication performance

, 2007
Seventy second-year medical students volunteered to participate in a study with the aim of evaluating the impact of the assessment of simulated bad news consultations on their physiological and psychological stress and communication performance ...
Cate, O. ten, Stress and self-regulation, Dulmen, S., Grosfeld, F., Bensing, J., Afd Klinische psychologie, Dulmen, S. van, ten Cate, Th.J., Bensing, J.M., Tromp, F.   +9 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Manganese nutrient mitigates ammonia, arsenic toxicity and high temperature stress using gene regulation via NFkB mechanism in fish

Scientific Reports
The ongoing challenges of climate change and pollution are major factors disturbing ecosystems, including aquatic systems. They also have an impact on gene regulation and biochemical changes in aquatic animals, including fish.
Neeraj Kumar, Supriya Tukaram Thorat, Sanjivkumar Angadrao Kochewad, Kotha Sammi Reddy   +3 more
doaj   +1 more source

A parallel investigation of trauma exposure, maladaptive appraisals and posttraumatic stress reactions in two groups of trauma-exposed adolescents

European Journal of Psychotraumatology
Background: Maladaptive appraisals, such as thoughts about experiencing a permanent and disturbing change and about being a fragile person in a scary world, are associated with posttraumatic stress reactions (PTSR) for trauma-exposed children and ...
Andrea Undset, Tine K. Jensen, Grete Dyb, Tore Wentzel-Larsen, Silje M. Ormhaug, Synne Stensland, Ines Blix   +6 more
doaj   +1 more source

Perceived stress, stress management, and vigorous physical activity among college students

, 2013
textObesity is a public health concern and obesity rates increase from adolescence to adulthood. Therefore, the period between 18-24, known as emerging adulthood, may be a crucial period in the development of obesity.
Yingling, Camille E
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Effect of artificial and natural diets on the morphometrics and biology of Sesamia inferens (Walker) (Lepidoptera: Noctuidae)

Journal of Basic and Applied Zoology
Background Sesamia inferens is a polyphagous pest severely impacting gramineous crops (e.g., rice, wheat, maize) across Asia, causing "dead heart" and "white ear" damage.
M. Chethankumar, Mallikarjuna Jeer, K. C. Sharma, Yogesh Yele   +3 more
doaj   +1 more source

Micro/nanoplastics pollution: emerging challenges for aquatic animals and food crops

Frontiers in Toxicology
Recent reports from worldwide reveal that micro/nanoplastics (MNPs) are pervasive pollutants affecting all ecosystems and a wide range of organisms, including animals, plants, fish, humans, and microorganisms.
Shrutarshee Kundu, Neeraj Kumar, Paritosh Kumar, Basavaraj PS, Ajay Kumar Singh, Dipti Godse, Kotha Sammi Reddy   +6 more
doaj   +1 more source