Results 111 to 120 of about 5,060,804 (319)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Posttraumatic stress disorder : scientific and professional dimensions /
This comprehensive overview of research and clinical practice in PTSD includes new insights into assessment with regard to DSM-5 and ICD-11, discussion of ongoing controversies in the field as to what constitutes safe and effective care, and new research
Ford, Julian D.,author. +4 more
core
Stress perception and production in German stress clash environments
, 2002 Wagner P, Fischenbeck E. Stress perception and production in German stress clash environments. In: Proceedings of Speech Prosody 2002. Aix en Provence, France; 2002.Several production and perception experiments have been carried out in order to ...
Wagner, Petra ; https://orcid.org/ +1 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
European Journal of PsychotraumatologyBackground: After exposure to a potentially traumatic event, survivors may experience thoughts about ‘what could have happened’, referred to as counterfactual thoughts (CFTs).
Ines Blix +6 more
doaj +1 more source
Effect of Stress During Voluntary Blinking
, 2007 The purpose of this study was to investigate the effect of stress during voluntary blinking. Voluntary blinking was examined under two different conditions. One was a period during which voluntary blinking was performed 60 times per minute. The other was
田中, 裕, TANAKA, Yu, 492, 493
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Genome BiologyBackground The histone code, comprised of diverse histone post-translational modifications, intricately regulates nucleosome organization and gene expression. Histone marks also serve as binding sites for a diverse array of protein complexes and enzymes,
Rubén Barrios +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source