Results 121 to 130 of about 5,060,804 (319)
BMC PsychologyBackground Moral injury can follow exposure to three types of potentially morally injurious event (PMIE). Both PMIE exposure and moral injury are associated with poor health and functioning outcomes.
Gavin M. Campbell +3 more
doaj +1 more source
Job-related stress and burnout
, 2002 Occupational stress is a topic of substantial interest to organizational researchers and managers, as well as society at large. Stress arising from work conditions can be pervasive and significant in its impact on individuals, their families and ...
Cooper, Cary L. +1 more
core
Perinatal stress and anxiety in Ireland: experiences and support needs
Objectives: Perinatal stress and anxiety from conception to two years postpartum have important adverse outcomes for women and infants. This study examined (i) women's perception of sources and experiences of perinatal stress and anxiety, (ii) women's ...
Looney, Eibhlin +3 more
core +1 more source
Stress and cardiac beta adrenoceptors
, 2006 Most modern theories about stress recognize that although stress is not a disease, it may be the trigger for the majority of diseases when allostatic overload has been generated.
Santos, Iraides N. +1 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Mechanical Behaviour of Materials: Stress analysis and Mohr's circle
, 2010 This set of animations explains how to use the Mohr's circle in stress analysis.
DoITPoMS, University of Cambridge +3 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Homework stress in children and adolescents [PDF]
openL'elaborato riguarda lo stress da compiti scolastici in bambini ed adolescenti. A seguito di una breve panoramica in alcune culture e nei soggetti con diagnosi di DSA, si analizzano poi i fattori implicati in questa particolare tipologia di stress e ...
FIDANZI, BIANCA
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source