Results 151 to 160 of about 10,727,912 (338)

Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes

, 2018
Elizabeth F. Sutton, Robbie A. Beyl, Kate Early, William T. Cefalu, Éric Ravussin, Courtney M. Peterson   +5 more
openalex   +2 more sources

Cyclin-dependent Kinase E1 (CDKE1) Provides a Cellular Switch in Plants between Growth and Stress Responses [PDF]

, 2012
Sophia Ng, Estelle Giraud, Owen Duncan, Simon R. Law, Yan Wang, Xu Lin, Reena Narsai, Chris Carrie, Hayden Walker, David A. Day, Nicolás E. Blanco, Åsa Strand, James Whelan, Aneta Ivanova   +13 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Association of potential morally injurious events, moral injury and somatic symptoms of health in UK military veterans: a cross-sectional study

BMC Psychology
Background Moral injury can follow exposure to three types of potentially morally injurious event (PMIE). Both PMIE exposure and moral injury are associated with poor health and functioning outcomes.
Gavin M. Campbell, Natasha Biscoe, Amanda Bonson, Dominic Murphy   +3 more
doaj   +1 more source

Expression Profiling of Tobacco Leaf Trichomes Identifies Genes for Biotic and Abiotic Stresses [PDF]

, 2010
Emiko Harada, Ji‐Ah Kim, Andreas J. Meyer, Rüdiger Hell, Stephan Clemens, Yong-Eui Choi   +5 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Neural and behavioral markers of inhibitory control predict symptom improvement during internet-delivered cognitive behavioral therapy for depression

Translational Psychiatry
Poor inhibitory control contributes to deficits in emotion regulation, which are often targeted by treatments for major depressive disorder (MDD), including cognitive behavioral therapy (CBT).
Michelle Thai, Elizabeth A. Olson, Stefanie Nickels, Daniel G. Dillon, Christian A. Webb, Boyu Ren, William D. S. Killgore, Scott L. Rauch, Isabelle M. Rosso, Diego A. Pizzagalli   +9 more
doaj   +1 more source

Etiologies of sperm oxidative stress

, 2016
Parvin Sabeti, Soheila Pourmasumi, Tahereh Rahiminia, Fatemeh Akyash, Ali Reza Talebi   +4 more
openalex   +1 more source

Propagating Stress Waves During Epithelial Expansion [PDF]

, 2015
Shiladitya Banerjee, Kazage J Christophe Utuje, M. Cristina Marchetti   +2 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source