Results 151 to 160 of about 7,573,455 (296)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Stress—Its Definition [PDF]

, 1901
R. F. Muirhead
openalex   +1 more source

Decoding the CBL gene family in durum wheat: Insights into dual ABA signaling pathways and calcium-mediated drought tolerance. [PDF]

Plant Genome
Hosseini Pouya HS, Cheniany M, Heidari P.   +2 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

The Stresses in Masonry Dams [PDF]

, 1908
E. H. Brown
openalex   +1 more source

Evaluation of Transport Time on Stress Biomarkers in Pigs. [PDF]

Vet Med Sci
Currie S, Swindle MM, Suckow MA, Zhang JQ, Adusumilli S.   +4 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Effect of Stress on Hole Formation during the Diffusion of Zinc from Brass in vacuo [PDF]

, 1957
L. M. T. Hopkin
openalex   +1 more source

Enduring the Unbearable-A Phenomenological Hermeneutical Study on Nurses' Lived Experiences of Stress During the COVID-19 Pandemic. [PDF]

Scand J Caring Sci
Carnesten H, von Heideken Wågert P, Wiklund Gustin L, Skoglund K, Andreae C.   +4 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source