FEBS Open Bio, EarlyView.Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi +5 more
wiley +1 more source
Most autophagic cell death studies lack evidence of causality
FEBS Open Bio, EarlyView.Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
Effectiveness of a Parent Empowerment Program for Parents of Children with Autism: A Randomized Controlled Trial. [PDF]
Child Care Health DevŞahin Büyük D, Özmen D.
europepmc +1 more source
Beyond p‐values: Assessing clinical significance in acupuncture research
Advanced Chinese Medicine, EarlyView.Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley +1 more source
The Influence of a Multimodal Cognitive Behavioural Intervention on the Stress Mindset, Psychological Wellbeing, and Performance of Students Aged 16-18 Facing Exams. [PDF]
Stress HealthSparks KV +3 more
europepmc +1 more source
THE EFFECT OF TRANSFORMATION AND THERMAL CONTRACTION ON THE QUENCHING STRESS OF STEEL
, 1950 Takeshi Sugeno, Koshiro Sakamoto
openalex +2 more sources
Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC).
Monica Margoni +7 more
wiley +1 more source
Investigation of parallel joint density thresholds for granite tunnel failure based on physical model experiments and multiscale monitoring techniques. [PDF]
Sci RepXu HS +6 more
europepmc +1 more source
Fatigue Strength of Metallic Materials under Varying Repeated Stresses
, 1957 Toshiro Yamada
openalex +2 more sources