Results 301 to 310 of about 10,382,141 (339)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Genome-wide characterization of NHX gene family in Medicago sativa under abiotic stress. [PDF]

open access: yesBMC Plant Biol
Zhang Y   +10 more
europepmc   +1 more source

A stress-free stress response

Nature Chemical Biology, 2020
A new molecule that specifically activates a key protein homeostasis pathway has been identified. The ability to initiate the IRE1–XBP1s branch of the unfolded protein response opens up new avenues for basic research and treatment of disease.
Nadia Cummins, Rebecca C. Taylor
openaire   +4 more sources

Stress and Stress Reduction

Clinical Obstetrics & Gynecology, 2014
Chronic stress contributes to preterm birth (PTB), through direct physiological mechanisms or behavioral pathways. This review identified interventions to prevent PTB through decreased maternal stress. Studies were grouped according to intervention: group prenatal care (11 studies), care coordination (8 studies), health insurance expansion (4 studies),
Sameen Qadir   +3 more
openaire   +3 more sources

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