Results 61 to 70 of about 6,476,644 (264)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
ModellingThis research aims to study the mechanical behavior of the materials most commonly used in crankshaft manufacturing by designing a four-piston crankshaft, analyzing the stresses and displacements resulting from the applied load, and determining vibration
Hasan Mhd Nazha +4 more
doaj +1 more source
Computer aided structural analysis of newly developed railway bogie frame
MATEC Web of Conferences, 2018 The paper is part of the publication series, which describe the most significant and innovative research and development design solutions and computational procedures as part of European structural funds project.
Šťastniak Pavol +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Using Keystroke Dynamics in a Multi-Agent System for User Guiding in Online Social Networks
Applied Sciences, 2020 Nowadays there is a strong integration of online social platforms and applications with our daily life. Such interactions can make risks arise and compromise the information we share, thereby leading to privacy issues. In this work, a proposal that makes
Guillem Aguado +3 more
doaj +1 more source
Stress relaxation and elastic follow-up using a stress range-dependent constitutive model [PDF]
, 2012 Despite the availability of detailed nonlinear finite element analysis, some aspects of high temperature design can still be best addressed through more simplified methods.
Boyle, James
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
On the Energy Storage Capacity and Design Optimization of Compound Flywheel Rotors with Prestressed Hyperbolic Disks [PDF]
Journal of Applied and Computational MechanicsFlywheels used for energy storage may be assembled by press fitting or bonding of concentric rotor parts. During operation, each part is subjected to a superposition of stress fields associated with centrifugal loading and with contact at the component ...
Sutham Arun +3 more
doaj +1 more source
In a study of the validity of eight candidate voice measures (fundamental frequency, amplitude, speech rate, frequency jitter, amplitude shimmer, Psychological Stress Evaluator scores, energy distribution, and the derived measure of the above measures ...
Brenner, Malcolm, Shipp, Thomas
core +1 more source
Prospective Analysis of Stress and Immunity in Advanced Cancer [PDF]
, 2011 Objectives:The aims of this study were to assess chronic stress in a sample of advanced cancer patients, test the association between stress and NK cell immune markers over time, and examine whether stress predicts immune markers over time.Methods:A ...
Ikpeama, Uzoh Erick
core +1 more source