Results 61 to 70 of about 6,427,335 (253)

High temperature stress-strain analysis [PDF]

open access: yes
The objectives of the high-temperature structures program are threefold: to assist in the development of analytical tools needed to improve design analyses and procedures for the efficient and accurate prediction of the nonlinear structural response of ...
Moorhead, Paul E., Thompson, Robert L.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Analysis of silicon stress/strain relationships [PDF]

open access: yes
In the study of stress-strain relationships in silicon ribbon, numerous solutions were calculated for stresses, strain rates, and dislocation densities through the use of the Sumino model. It was concluded that many cases of failure of computer solutions
Dillon, O.
core   +2 more sources

Stress Analysis of Prithvi Missil Wing Subjected to Aerodynamic Forces [PDF]

open access: yes, 1988
The stress problem of Prithvi missile wing is investigated . The analysis is carried out by the finite element method by using the ASKA software package.
Ashok Kamath, .   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A study on task difficulty and acceleration stress [PDF]

open access: yes, 1981
The results of two experiments which relate to task difficulty and the effects of environmental stress on tracking performance are discussed and compared to subjective evaluations.
Repperger, D. W., Rogers, D. B.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Wind stress and its dependence on wind speed and sea state [PDF]

open access: yes, 1992
The aim of the project is to detect and quantify the effect of sea state on the wind stress. An overview of the basic theory of wind stress in the surface layer is provided, along with a more detailed description of the inertial dissipation method which ...
Yelland, M.J.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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