Results 81 to 90 of about 6,447,976 (288)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Communications, 2012 The article deals with the determining of fatigue lifetime of structural materials during multiaxial cyclic loading. The aim of this investigation is to evaluate the influence on fatigue behavior of the welded aluminum alloy EN AW 6063-T66.
Peter Kopas, Milan Saga, Milan Uhricik
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
In plane stress analysis [PDF]
An investigation of the blowing up of UK numerical results for the inplane stress calculations for silicon ribbon is presented. The inplane stress that exists in a thin plate is governed by two general equations of equilibrium and ...
Dillon, O. W., Jr.
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Prospective Analysis of Stress and Immunity in Advanced Cancer [PDF]
, 2011 Objectives:The aims of this study were to assess chronic stress in a sample of advanced cancer patients, test the association between stress and NK cell immune markers over time, and examine whether stress predicts immune markers over time.Methods:A ...
Ikpeama, Uzoh Erick
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Contact effects in bending affecting stress and formability [PDF]
, 2010 If a strip is pulled over a curved tool there is a contact stress acting on the strip. This contact stress changes the stress state in the material, which is analysed with a simple model.
Boogaard, A.H. van den, Emmens, W.C.
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
BuildingsThis study aims to investigate the mechanical response of a submarine concrete pipeline under wave action in shallow waters, taking into account factors such as the compressibility of pores and the permeability of the seabed.
Haiyan Ju +5 more
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Nihon Kikai Gakkai ronbunshu, 2018 Weld-joint has been atracting attention to assemble structures of dissimilar metals, particularly in automobile industry. However, the application of weld-joint to steel and aluminum plates is still limited due to uncertainty of the fatigue strength ...
Kosuke TAKAHASHI +6 more
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