Results 101 to 110 of about 2,595,495 (302)

Challenges and Future Perspectives of Multi-/Hyperspectral Thermal Infrared Remote Sensing for Crop Water-Stress Detection: A Review

open access: yesRemote Sensing, 2019
Thermal infrared (TIR) multi-/hyperspectral and sun-induced fluorescence (SIF) approaches together with classic solar-reflective (visible, near-, and shortwave infrared reflectance (VNIR)/SWIR) hyperspectral remote sensing form the latest state-of-the ...
Max Gerhards   +3 more
doaj   +1 more source

Modeling of human physiological stresses: A thermodynamics-based approach

open access: yesOccupational Ergonomics, 2006
This paper discusses thermodynamic basis for quantifying human physiological stresses. The deterministic nature of the second law of thermodynamics (entropy approach) and classical Maxwell relations were used to develop formulas to quantify human stress due to the artifact-human interactions.
Boregowda, Satish C.   +1 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Modeling and simulation of residual stress in metal cutting process: A review

open access: yesAdvances in Mechanical Engineering
Due to the complexity of analyzing residual stress, which involves numerous cutting parameters encompassing both mechanical and thermal stresses, various modeling and simulation methods, including analytical, numerical, and machine learning approaches ...
Ruihu Zhou
doaj   +1 more source

Psychotherapy for complex post-traumatic stress disorder: efficacy and therapeutic factors

open access: yesFrontiers in Psychology
The treatment of patients with complex post-traumatic stress disorder (CPTSD) presents significant challenges due to the complexity and severity of the condition.
Cenya Katalan   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Oxidative stress in cancer: from tumor and microenvironment remodeling to therapeutic frontiers

open access: yesMolecular Cancer
Oxidative stress is a pathological condition of redox signaling dysregulation and macromolecular oxidative damage arising from elevated ROS levels. Oxidative stress interacts with tumor cell growth regulation and tumor microenvironment remodeling, and ...
Xisong Liang   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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