Results 111 to 120 of about 2,595,495 (302)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Literature review of scenario methods. W.P. 5-W.P. 4 D.3 final (version 1) [PDF]
, 2006 This document is a literature review of scenario methods elaborated in the frame of ADD TRANS project (2005-2009) . Within this project, WP4 is aimed at the assessment of land use change at the farm level and its impacts on the territory and WP5 is aimed
Gibon, Annick (ed.), Simon, C.
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Phenotypic and molecular plasticity of two eucalypts clones in response to water deficit: An integrated approach [PDF]
, 2010 In the context of climate change, water availability will be the main limiting factor affecting biomass production, in particular in intensively managed forest tree plantations.
Bedon, Franck +8 more
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Some consequences of stress range dependent constitutive models in creep [PDF]
, 2010 Studies of the behaviour of structural components at high temperature subject to creep have a long history and their behavioural characteristics, certainly for constant and cyclic load, well established.
Boyle, James
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The effect of corrosive environment on fatigue life and on mean stress sensitivity factor
MATEC Web of Conferences, 2018 An experimental investigation of the effect of corrosive environment on the fatigue life of circular cross section specimens made from structural low carbon steel S355 is presented in this paper.
Morgantini Marta +3 more
doaj +1 more source
The nonlinear viscoelastic response of resin matrix composite laminates [PDF]
Possible treatments of the nonlinear viscoelastic behavior of materials are reviewed. A thermodynamic based approach, developed by Schapery, is discussed and used to interpret the nonlinear viscoelastic response of a graphite epoxy laminate, T300/934 ...
Brinson, H. F., Cardon, A. H., Hiel, C.
core +1 more source