Results 181 to 190 of about 2,696,756 (302)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Influence of Framework Material and Posterior Implant Angulation in Full-Arch All-on-4 Implant-Supported Prosthesis Stress Concentration. [PDF]

Dent J (Basel), 2022
Tribst JPM, Campanelli de Morais D, Melo de Matos JD, Lopes GDRS, Dal Piva AMO, Souto Borges AL, Bottino MA, Lanzotti A, Martorelli M, Ausiello P.   +9 more
europepmc   +1 more source

STRESS CONCENTRATION DURING TWISTING [PDF]

Vìsnik L’vìvs’kogo nacìonal’nogo agrarnogo unìversitetu. Arhìtektura ì sìl’s’kogospodars’ke budìvnictvo, 2017
T. Bubnjak, J. Famulak
openaire   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Engagement and Stress Concentration Evaluation of a Novel Two-Part Compression Screw: A Preliminary Finite Element Analysis. [PDF]

Bioengineering (Basel)
Hsu CH, Wang CK, Wang YH, Lin SY, Lu CC, Fu YC, Huang HT, Chen CH, Chou PH.   +8 more
europepmc   +1 more source

Stress Concentration Factors for Welded Plate T-Joints Subjected to Tensile, Bending, and Shearing Loads. [PDF]

Materials (Basel), 2021
Molski KL, Tarasiuk P.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

The evolution law of mining stress concentration effect and mining pressure manifestation mechanism under different pushing methods in valley landforms. [PDF]

Sci Rep
Fu P, Luo J, Yan S, Mu J.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Effects of Pore Defects on Stress Concentration of Laser Melting Deposition-Manufactured AlSi10Mg via Crystal Plasticity Finite Element Method. [PDF]

Materials (Basel)
Zhang W, Liu J, Xing Y, Ao X, Yang R, Yang C, Tan J.   +6 more
europepmc   +1 more source