Results 161 to 170 of about 1,334,534 (307)

Stress Concentration Analysis of the Corroded Steel Plate Strengthened with Carbon Fiber Reinforced Polymer (CFRP) Plates. [PDF]

Polymers (Basel), 2022
Li A, Wang H, Li H, Kong D, Xu S.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Multi-physics Simulation of Electrical Contacts: Coupled Mechanical and Thermal Analysis Using ANSYS [PDF]

Journal of Electrical and Electronics Engineering
This study presents a finite element analysis of an electrical contact using ANSYS, focusing on both mechanical and thermal behavior. A silver–copper contact model was analyzed under loading to assess stress, deformation, and strain energy distributions.
TOMSE Andrei-Dan, MOLNAR Carmen-Otilia
doaj  

Magnetoacoustic Wave Scattering and Dynamic Stress Concentration around the Elliptical Opening in Exponential-Gradient Piezomagnetic Materials. [PDF]

Materials (Basel), 2022
Wang Z, Zhou C, Zhang X, Han X, Bao J, Chen L, Wang M, Gong Y, Zhou W.   +8 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Stress Concentration Factors of Concrete-Filled T-Joints under In-Plane Bending: Experiments, FE Analysis and Formulae. [PDF]

Materials (Basel), 2022
Matti F, Mashiri F.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The Effect of Lag Screw Position on Rotational Stability and Stress Concentration in Unstable Basicervical Intertrochanteric Fractures: A Finite Element Analysis. [PDF]

J Clin Med
Lee SW, Kim MS, Lee SJ, Kwak DK, Yoo JH.
europepmc   +1 more source

Scattering of Magnetoacoustic Waves and Dynamic Stress Concentration around Double Openings in Piezomagnetic Composites. [PDF]

Materials (Basel), 2021
Xue H, Zhou C, Cheng G, Bao J, Wang M, Gong Y, Ji H, Yang W, Hou B, Zhou W, Wang Q, Ni J.   +11 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source