Results 141 to 150 of about 11,866,665 (347)

Photoelasticity for Stress Concentration Analysis in Dentistry and Medicine. [PDF]

Materials (Basel), 2022
Marín-Miranda M, Wintergerst AM, Moreno-Vargas YA, Juárez-López MLA, Tavera-Ruiz C.   +4 more
europepmc   +1 more source

Biologic response of animals to husbandry stress with implications for biomedical models

, 2010
Peer-reviewedThe quality of life of animals is defined by a range of parameters including health, physiology, and behavior. Stress is defined as any damaging strain, force, or agent which stimulates a physiologic defense reaction and is capable under ...
Buckham-Sporer, Kelly, Pang, Wanyong, Gupta, Sandeep, Earley, Bernadette, Ting, Simon   +4 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Stress concentration. Introduction to stress concentration.

Journal of the Japan Welding Society, 1985
openaire   +3 more sources

Study on notch tensile properties of Fe-Mn-Si shape memory alloy

Materials Research Express
In order to investigate the effect of stress concentration on the mechanical properties of Fe-Mn-Si shape memory alloy, Fe17Mn5Si10Cr5Ni shape memory alloy was selected as the research object in this study.
Haojie Niu, Yubin Sun, Chengxin Lin
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Nonlinear Energy Harvesting by Piezoelectric Bionic 'M' Shape Generating Beam Featured in Reducing Stress Concentration. [PDF]

Micromachines (Basel), 2023
Xiong C, Wu N, He Y, Cai Y, Zeng X, Jin P, Lai M.   +6 more
europepmc   +1 more source

Effect of Acute Psychological Stress on Prefrontal GABA Concentration Determined by Proton Magnetic Resonance Spectroscopy

, 2010
Objective Impaired function of the central gamma-aminobutyric acid (GABA) system, which provides the brain’s major inhibitory pathways, is thought to play an important role in the pathophysiology of anxiety disorders.
Shen, Jun, van der Veen, Jan Willem, Gregor Hasler, Jun Shen, Hasler, Gregor, Drevets, Wayne C, Grillon, Christian, Christian Grillon, Jan Willem van der Veen, Wayne C. Drevets   +9 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The influence of surface roughness characteristics on fatigue stress concentration

, 2013
Numerical simulations have been performed to analyze the influence of surface roughness on the fatigue stress concentration with finite element method(FEM).The parameters to characterize the rough surface topology are analyzed,and the inherent ...
Zhang JF(张均锋), Li Q(李谦), Mu D(穆丹), Bian XD(卞祥德)   +3 more
core