On Shaft Fillet Stress Concentration [PDF]
, 2017 A shaft is typically loaded by three different load types; torsional, bending and normal load separately or more generally in combinations. In most cases the size of the shaft is controlled by the constraints on the maximum allowable deflection and ...
Pedersen, Niels Leergaard
core
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Effective Notch-Stress-Based Stress Concentration Factors of the Rib-Deck Weld in Orthotropic Steel Decks Considering the Effect of Asphalt Surfacing. [PDF]
Materials (Basel), 2023 Wang Q, Shi S, Yao Y, Wang Z, Fu Z.
europepmc +1 more source
Stress Concentration Factors From Overlapping Stress Fields in Uniaxial Tension
, 1976 Standard transmission photoelastic techniques were used to determine the resultant stress concentration factors produced by multiple stress raisers in flat, rectangular bars under uniaxial tension.
C. C. Yang +2 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Experimental and Numerical Study on the Influence of Stress Concentration on the Flexural Stability of an Aluminium Hollow Tube. [PDF]
Materials (Basel), 2023 Radhakrishnan G +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Awareness of Stress Concentration Points for Prevention and Management of Periprosthetic Fractures Following Plate Installation Reinforcement: A Case Report. [PDF]
J Orthop Case Rep, 2023 Taniguchi H, Yoshimoto N, Okazaki K.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A Bio-Inspired Bistable Piezoelectric Structure for Low-Frequency Energy Harvesting Applied to Reduce Stress Concentration. [PDF]
Micromachines (Basel), 2023 Wu N, Fu J, Xiong C.
europepmc +1 more source