Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Multi-physics Simulation of Electrical Contacts: Coupled Mechanical and Thermal Analysis Using ANSYS [PDF]
Journal of Electrical and Electronics EngineeringThis study presents a finite element analysis of an electrical contact using ANSYS, focusing on both mechanical and thermal behavior. A silver–copper contact model was analyzed under loading to assess stress, deformation, and strain energy distributions.
TOMSE Andrei-Dan, MOLNAR Carmen-Otilia
doaj
Numerical Modeling of the Effect of Cutting-Edge Radius on Cutting Force and Stress Concentration during Machining. [PDF]
Micromachines (Basel), 2022 Li P, Chang Z.
europepmc +1 more source
Joint design for improved fatigue life of diffusion-bonded box-stiffened panels [PDF]
Simple photoelastic models were used to identify a cross-section geometry that would eliminate the severe stress concentrations at the bond line between box stiffeners diffusion bonded to a panel skin.
Davis, R. C. +2 more
core +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Scattering of Magnetoacoustic Waves and Dynamic Stress Concentration around Double Openings in Piezomagnetic Composites. [PDF]
Materials (Basel), 2021 Xue H +11 more
europepmc +1 more source
The effect of broken stringers on the stress intensity factor for a uniformly stiffened sheet containing a crack [PDF]
A linear elastic stress analysis was made of a centrally cracked sheet stiffened by riveted, uniformly spaced and sized stringers. The stress intensity factor for the sheet and the load concentration factor for the most highly loaded stringer were ...
Poe, C. C., Jr.
core +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Urethane-Foam-Embedded Silicon Pressure Sensors including Stress-Concentration Packaging Structure for Driver Posture Monitoring. [PDF]
Sensors (Basel), 2022 Takamatsu S, Sato S, Itoh T.
europepmc +1 more source
Stress concentration. Introduction to stress concentration.
Journal of the Japan Welding Society, 1985 openaire +2 more sources