Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Assessment of residual stress using thermoelastic stress analysis
, 2011 The work described in this thesis considers the application of thermoelastic stress analysis (TSA) to theassessment of residual stresses in metallic materials. Residual stresses exist within almost all engineeringcomponents and structures.
Robinson, Andrew Ferrand
core +1 more source
Stress Concentration Factors in Excavation Repairs of Surface Defects in Forgings and Castings. [PDF]
Materials (Basel), 2022 Rebora A, Torre G, Vernassa G.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Microstructure, Fatigue Properties and Stress Concentration Analysis of 6005 Aluminum Alloy MIG Welded Lap Joint. [PDF]
Materials (Basel), 2022 Li Y, Yang S, Peng Z, Wang Z, Gao Z.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Effect of Antirotational Two-Piece Titanium Base on the Vertical Misfit, Fatigue Behavior, Stress Concentration, and Fracture Load of Implant-Supported Zirconia Crowns. [PDF]
Materials (Basel), 2023 Adolfi D +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Stress Concentration Analysis of the Corroded Steel Plate Strengthened with Carbon Fiber Reinforced Polymer (CFRP) Plates. [PDF]
Polymers (Basel), 2022 Li A, Wang H, Li H, Kong D, Xu S.
europepmc +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source