Results 131 to 140 of about 1,334,534 (307)

Stress testing credit risk: a survey of authorities' approaches [PDF]

This paper reviews the quantitative methods used at selected central banks to stress testing credit risk, focusing in particular on the methods used to link macroeconomic drivers of stress with bank specific measures of credit risk (macro stress test ...
Antonella Foglia
core  

Photoelasticity for Stress Concentration Analysis in Dentistry and Medicine. [PDF]

Materials (Basel), 2022
Marín-Miranda M, Wintergerst AM, Moreno-Vargas YA, Juárez-López MLA, Tavera-Ruiz C.   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Stress concentration. Introduction to stress concentration.

Journal of the Japan Welding Society, 1985
openaire   +3 more sources

Functionally‐Graded Serrated Fangs Allow Spiders to Mechanically Cut Silk, Carbon and Kevlar Fibers

Advanced Science
Before humans and allegedly any animal group, spiders developed “functionally graded toothed blades” that cut one of the toughest biological materials: silk.
Gabriele Greco, Diego Misseroni, Filippo Castellucci, Nicolò G. Di Novo, Nicola M. Pugno   +4 more
doaj   +1 more source

Numerical Simulation of Mechanical Properties of Non-Standard Rock Specimens Under Uniaxial Compression

Applied Sciences
Uniaxial compression testing provides essential mechanical property characterization for intact rock specimens. The accuracy of specimen preparation critically affects compression test results through end-surface geometry deviations: parallelism ...
Fangcai Zhu, Ling Sun, Mengchang Ma, Jiang Guo, Xuebin Xie   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Study on notch tensile properties of Fe-Mn-Si shape memory alloy

Materials Research Express
In order to investigate the effect of stress concentration on the mechanical properties of Fe-Mn-Si shape memory alloy, Fe17Mn5Si10Cr5Ni shape memory alloy was selected as the research object in this study.
Haojie Niu, Yubin Sun, Chengxin Lin
doaj   +1 more source

Nonlinear Energy Harvesting by Piezoelectric Bionic 'M' Shape Generating Beam Featured in Reducing Stress Concentration. [PDF]

Micromachines (Basel), 2023
Xiong C, Wu N, He Y, Cai Y, Zeng X, Jin P, Lai M.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source