Results 111 to 120 of about 2,696,756 (302)

Numerical and experimental modelling of carrying elements of heavy metallurgical equipments [PDF]

Metalurgija, 2010
Carrying structures of heavy metallurgical equipments are during their operation often exposed to extreme loading. The short-term overloading of the structure results to high stresses in locations of their concentrations.
F. Trebuňa, F. Šimčák, A. Gmiterko
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Photoelasticity for Stress Concentration Analysis in Dentistry and Medicine. [PDF]

Materials (Basel), 2022
Marín-Miranda M, Wintergerst AM, Moreno-Vargas YA, Juárez-López MLA, Tavera-Ruiz C.   +4 more
europepmc   +1 more source

Stress concentration effects in micropolar elasticity Technical report no. 8-4 [PDF]

Stress concentration around circular hole in infinite plate subject to axial ...
Ariman, T., Kaloni, P. N.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Failure Mechanisms of Basalt Fiber Concrete Under Splitting Tensile Tests and DEM Simulations

Buildings
To address the cracking problem caused by the weak tensile performance of concrete, this study investigates the failure mechanisms of basalt fiber-reinforced concrete under different fiber contents, single-blend, and mixed-blend schemes through splitting
Linlin Jiang, Chuan Zhao, Shaoxiong Zhang, Mingyue Qiu, Ruitong Zhang, Yifei Li, Wenbing Zhang, Shuyang Yu   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Nonlinear Energy Harvesting by Piezoelectric Bionic 'M' Shape Generating Beam Featured in Reducing Stress Concentration. [PDF]

Micromachines (Basel), 2023
Xiong C, Wu N, He Y, Cai Y, Zeng X, Jin P, Lai M.   +6 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Functionally‐Graded Serrated Fangs Allow Spiders to Mechanically Cut Silk, Carbon and Kevlar Fibers

Advanced Science
Before humans and allegedly any animal group, spiders developed “functionally graded toothed blades” that cut one of the toughest biological materials: silk.
Gabriele Greco, Diego Misseroni, Filippo Castellucci, Nicolò G. Di Novo, Nicola M. Pugno   +4 more
doaj   +1 more source