Results 111 to 120 of about 6,289,847 (284)

Photoelasticity for Stress Concentration Analysis in Dentistry and Medicine. [PDF]

Materials (Basel), 2022
Marín-Miranda M, Wintergerst AM, Moreno-Vargas YA, Juárez-López MLA, Tavera-Ruiz C.   +4 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Stress concentration. Introduction to stress concentration.

JOURNAL OF THE JAPAN WELDING SOCIETY, 1985
openaire   +3 more sources

Failure Mechanisms of Basalt Fiber Concrete Under Splitting Tensile Tests and DEM Simulations

Buildings
To address the cracking problem caused by the weak tensile performance of concrete, this study investigates the failure mechanisms of basalt fiber-reinforced concrete under different fiber contents, single-blend, and mixed-blend schemes through splitting
Linlin Jiang, Chuan Zhao, Shaoxiong Zhang, Mingyue Qiu, Ruitong Zhang, Yifei Li, Wenbing Zhang, Shuyang Yu   +7 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Nonlinear Energy Harvesting by Piezoelectric Bionic 'M' Shape Generating Beam Featured in Reducing Stress Concentration. [PDF]

Micromachines (Basel), 2023
Xiong C, Wu N, He Y, Cai Y, Zeng X, Jin P, Lai M.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Functionally‐Graded Serrated Fangs Allow Spiders to Mechanically Cut Silk, Carbon and Kevlar Fibers

Advanced Science
Before humans and allegedly any animal group, spiders developed “functionally graded toothed blades” that cut one of the toughest biological materials: silk.
Gabriele Greco, Diego Misseroni, Filippo Castellucci, Nicolò G. Di Novo, Nicola M. Pugno   +4 more
doaj   +1 more source

Numerical Simulation of Mechanical Properties of Non-Standard Rock Specimens Under Uniaxial Compression

Applied Sciences
Uniaxial compression testing provides essential mechanical property characterization for intact rock specimens. The accuracy of specimen preparation critically affects compression test results through end-surface geometry deviations: parallelism ...
Fangcai Zhu, Ling Sun, Mengchang Ma, Jiang Guo, Xuebin Xie   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source