Results 201 to 210 of about 11,866,665 (347)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Failure modes affected by stress concentration in gneiss: laboratory triaxial experiment and numerical reproduction. [PDF]

Sci Rep
Guo L, Zhang B, Huang K, Song D, Chen J, Liu X, Zhang H, Xu G.   +7 more
europepmc   +1 more source

Material heterogeneity or stress concentration: the thermoelastic response from woven composite materials subjected to cyclic fatigue

, 2009
A study of the growth of fatigue damage in 2 x 2 twill woven composite materials, subjected to cyclic tensile loading are described. Thermoelastic stress analysis (TSA) is used to monitor the stress field.
Fruehmann, R.K., Quinn, S., Dulieu-Barton, J.M.   +2 more
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Stress concentration. Stress concentration from the viewpoint of welding operation.

Journal of the Japan Welding Society, 1985
openaire   +3 more sources

Scattering and dynamic stress concentration analysis of elastic waves around arbitrarily shaped holes in piezoelectric smart building materials. [PDF]

Sci Rep
Qi C, Zhao Y, Yang X, Xie Y, Yu X, Gai J, Meng Z, Zhai S, Gong R.   +8 more
europepmc   +1 more source

Stress concentration-relocating interposer in electronic textile packaging using thermoplastic elastic polyurethane film with via holes for bearing textile stretch. [PDF]

Sci Rep, 2022
Takamatsu S, Sato S, Itoh T.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Effect of occlusal anatomy of CAD/CAM feldspathic posterior crowns in the stress concentration and fracture load. [PDF]

Clin Exp Dent Res, 2021
Borges ALS, Tribst JPM, de Lima AL, Dal Piva AMO, Özcan M.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source