Results 101 to 110 of about 9,006,777 (290)

Childhood Traumatic Experiences and Post-Traumatic Stress Disorder in Female Adults: Which is the Role Played by Romantic Attachment? [PDF]

, 2016
Childhood traumatic experiences are known to have strong and durable e ects on physical, mental and reproductive health. One of the most studied consequences of childhood trauma is the post-traumatic stress disorder (PTSD).
Alessandra Simonelli, Chiara Sacchi, SACCHI, CHIARA, SIMONELLI, ALESSANDRA   +3 more
core   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

Advanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen, Haiyang Gao, Wang Wu, Pengzhi Shi, Yuhang Chen, Anran Zhang, Zhangrong Cheng, Wenbo Wu, Zimu Yu, Yukun Zhang   +9 more
wiley   +1 more source

The psychological impact of rape : a long longitudinal study of adult female survivors in the Western Cape, South Africa [PDF]

, 2013
Includes bibliographical references.There is a broad body of research which suggests that rape is highly pathogenic, most commonly described in terms of Post Traumatic Stress Disorder (PTSD).
Maw, Anastasia
core   +1 more source

Unveiling the link between stress-related disorders and autonomic dysfunction in Parkinson’s disease: a cross-sectional study

Revista Mexicana de Neurociencia
Objective: Recent evidence has underscored the detrimental effects of chronic stress on health, particularly its impact on neurodegenerative disorders such as Parkinson’s disease (PD).
Esrom J. Acosta-Epinoza, Daniela I. Salinas-Leal, Ilse A. Ortiz-Marroquin, Arnulfo González-Cantú, Mirna Gonzalez-Gonzalez, Daniel Martinez-Ramirez   +5 more
doaj  

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

Advanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou, Jiwei Sun, Peng Chen, Caihong Mao, Junyuan Zhang, Haoqi Lei, Xiaoqing Han, Yaxuan Zhang, Yuheng Jiang, Yulin Jia, Bin Su, Lili Chen   +11 more
wiley   +1 more source

Post-traumatic stress disorder: Case report [PDF]

, 2009
Following exposure to a major traumatic event like the August seventh 1998 Nairobi bomb blast various reactions occur, some of which result in stress-related psychiatric disorders.
Nyamai, CM, Njenga, FG, CM Nyamai, FG Njenga   +3 more
core   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

Advanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang, Bo Jin, Shipian Li, Qianxi Ouyang, Yu Xiao, Jiaxin Wen, Yehua Lai, Ping Wang, Yongjun Wang, Xuejun Cui, Weian Zhang, Min Yao   +11 more
wiley   +1 more source

Post-Traumatic Stress Symptoms in Caregivers: A Scoping Review

, 2023
The article seeks to explore whether post-traumatic stress symptoms are present in caregivers of individuals with mental health disorders, including neurodevelopmental, psychiatric, and neurocognitive ...
Barlas, Joanna, Kaur, Divjyot, Ng, Pamela, Lim, Jan Mei   +3 more
core   +1 more source

The mediating role of sleep in PTSD and positive/negative emotional states during the COVID-19 resurgence

Scientific Reports
This study aims to analyze the correlation between post-traumatic stress levels and positive/negative emotion among the public during public health emergency, and examine the mediating effect of sleep quality.
Liqun Qing, Xiangyue Wang, Jingzhou Xu, Lei Xiao, Hao Wang, Ruike Zhang, Shuyu Xu, Tong Su   +7 more
doaj   +1 more source