Results 91 to 100 of about 9,006,777 (290)

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Noradrenaline and Post-Traumatic Stress Disorder

, 2016
Noradrenaline (NA), a well known catecholamine has become the key transmitter involved in the generation of the autonomic symptoms present in the post-traumatic stress disorder (PTSD).
Hülya Cabadak, M. Zafer Gören
core   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

Advanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai, Wenxuan Qie, Xiaoye Li, Jingben Zheng, Ao He, Heng Dong, Jiangjiang Yan, Hao Zhang, Ziheng Pan, Hang Yin, Chuyi Zhou, Rui Kong, Hao Wang, Binghan Dai, Yannan Xie, Zhiqun Lin   +15 more
wiley   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Neuroepigenetics of Post-Traumatic Stress Disorder [PDF]

, 2018
While diagnosis of PTSD is based on behavioral symptom clusters that are most directly associated with brain function, epigenetic studies of PTSD in humans to date have been limited to peripheral tissues. Animal models of PTSD have been key for understanding the epigenetic alterations in the brain most directly relevant to endophenotypes of PTSD, in ...
Grace S, Kim, Alicia K, Smith, Caroline M, Nievergelt, Monica, Uddin   +3 more
openaire   +2 more sources

Traumatic Stress Disorders in Children and Adolescents

, 2012
Many children and adolescents who experience potentially traumatic events, such as natural disasters, acts of violence, physical injuries, child abuse, and life-threatening medical illnesses, display significant stress symptoms.
Whitney M. Herge, Herge, Whitney M, Annette M. La Greca, Cortney J. Taylor, Taylor, Cortney J, La Greca, Annette M   +5 more
core   +1 more source

Measuring symptoms of post-traumatic stress disorder in people with intellectual disabilities: the development and psychometric properties of the Impact of Event Scale – Intellectual Disabilities (IES-IDs) [PDF]

, 2014
Background: The aims of the study were to (a) revise the Impact of Event Scale – Revised for use with people with intellectual disabilities (IDs), creating the Impact of Event Scale – Intellectual Disabilities (IES-IDs), (b) assess the reliability of the
Langdon, Peter E., Langdon, Peter E.; id_orcid, Hall, JC, Hall, James C., Jobson, Laura   +4 more
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Recognizing post-traumatic stress disorder [PDF]

QJM: An International Journal of Medicine, 2004
Post-traumatic stress disorder (PTSD) is a severe and complex disorder precipitated by exposure to a psychologically distressing event. PTSD first appeared in the Diagnostic and Statistical Manual of Psychiatric Disorders (DSM-III) in 1980,1,,2 arising from studies of the Vietnam war, and of civilian victims of natural and man-made disasters.3,,4 ...
openaire   +2 more sources

The role of attachment in emotion regulation of traumatic stress

, 2011
Recent research has shown that there is a positive relationship between insecure attachment and psychopathology (van IJzendoorn, Bakermans-Kranenburg & Juffer, 2008).
Arikan, Gizem
core   +1 more source