Results 71 to 80 of about 9,006,777 (290)

Traumatic Stress Disorders in Children and Adolescents

, 2021
Youth’s exposure to natural disasters, acts of violence, motor vehicle accidents and other injuries, interpersonal violence, and life-threatening medical illnesses often leads to significant psychological distress.
Herge, Whitney M, Danzi, BreAnne A, La Greca, Annette M, Zimmerman, Cortney Taylor, Whitney M. Herge, Annette M. La Greca, Cortney Taylor Zimmerman, BreAnne A. Danzi   +7 more
core   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

Magnitude and factors associated with post-traumatic stress disorder among war-affected internally displaced people in northwest Ethiopia, 2022

SAGE Open Medicine
Background: A large number of people are often directly involved in armed conflict and, therefore, are at greater risk of developing a wide range of mental disorders, including post-traumatic stress disorder. Despite this, few have been reported about it
Gebresilassie Tadesse, Sewbesew Yitayih, Fanuel Gashaw, Setegn Fentahun, Agegnehu Amare, Getasew Kibralew, Tadele Amare Zeleke   +6 more
doaj   +1 more source

MicroRNAs in Post-traumatic Stress Disorder

, 2017
Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can develop following exposure to or witnessing of a (potentially) threatening event. A critical issue is to pinpoint the (neuro)biological mechanisms underlying the susceptibility to stress-related disorder such as PTSD, which develops in the minority of ~15% of individuals exposed ...
Snijders, Clara, de Nijs, Laurence, Baker, Dewleen G., Hauger, Richard L., van den Hove, Daniel, Kenis, Gunter, Nievergelt, Caroline M., Boks, Marco P., Vermetten, Eric, Gage, Fred H., Rutten, Bart P. F.   +10 more
openaire   +2 more sources

Evaluation of Post-Traumatic Stress Disorders [PDF]

Military Medicine, 2001
This paper introduces important considerations in the evaluation of psychological reactions to traumatic events. Proper assessment should include consideration of psychometric, cultural, and ethical issues. Mental disorders frequently observed in the aftermath of trauma (acute stress disorder and post-traumatic stress disorder) and stress (adjustment ...
openaire   +2 more sources

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

Advanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao, Yu‐Xin Zhang, Xiao‐Xing Liu, Zi‐Hang Li, Tang‐Sheng Lu, Jia‐Hui Deng, Wen Zhang, Peng Li, Xiao Lin, Shu‐Fei Feng, Ting‐Ting Li, Shi‐Qiu Meng, Xiang‐Dong Tang, Tian‐Ye Jia, Trevor W. Robbins, Jie Shi, Ying Han, Yan‐Xue Xue, Lin Lu, Kai Yuan   +19 more
wiley   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The interfaces between students' injuries, post-traumatic stress symptoms and eating disorders. [PDF]

, 2017
The aim of this study: To evaluate the interfaces between students' post-traumatic stress symptoms, injuries and eating disorders. Tasks of the research: 1. To evaluate students' gender differences in traumatic experiences 2.
Žeimys, Rokas,
core   +1 more source

Epidemiologic Study of Post-Traumatic Stress Disorder (PTSD) among Traffic Accident Victims in Tehran

مجله اپیدمیولوژی ایران, 2021
Background and Objectives: Road accidents are a major public health problem and one of the leading causes of death in the world. Some survivors of traffic accidents experience acute stress disorder and post-traumatic stress disorder during weeks to ...
H Soori, T Yousefinezhadi, E Haghighat Manesh   +2 more
doaj