Results 91 to 100 of about 3,638,288 (229)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Machine learning-based method for analyzing stress distribution in a ship. [PDF]

Sci Rep
Jin B, Zeng J, Xu L, Chen L, Zhan Y.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Influence of Various Implant Placement Strategies on Stress Distribution in Maxillary Implant-Retained Overdenture: A 3D Finite-Element Analysis. [PDF]

Clin Exp Dent Res
Ghorbani Z, Shojaei E, Neshandar Asli H, Falahchai M.   +3 more
europepmc   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Wall Shear Stress Distribution in Intracranial Atherosclerotic Disease and Associations With Vessel and Plaque Morphology. [PDF]

CNS Neurosci Ther
Lan L, Li S, Liu H, H L Ip V, Abrigo J, Tian X, Liu Y, Liu Y, Li Z, Liang T, Fan FSY, Ma SH, Ma K, Y M Ip B, Soo YOY, Leung H, Mok VCT, Fang H, Song B, Xu Y, Fan Y, Leung TW, Leng X.   +22 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Mechanical Properties of Dental Composites Modified with Liquid Rubber and Their Effect on Stress Distribution in Fillings. [PDF]

Materials (Basel)
Sowa M, Borkowski L, Pałka K.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Comparison of Giant Magnetoimpedance and Anisotropic Magnetoresistance Sensors for Residual Stress Distribution Determination in Magnetic Steels. [PDF]

Sensors (Basel)
Gudoshnikov S, Damatopoulou T, Hristoforou E.   +2 more
europepmc   +1 more source