Results 101 to 110 of about 3,700,086 (303)
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Editorial: Source and effects of light to moderate magnitude earthquakes – Volume II
J. M. Gaspar-Escribano +3 more
doaj +1 more source
Shear-Induced Stress Relaxation in a Two-Dimensional Wet Foam
We report on experimental measurements of the flow behavior of a wet, two-dimensional foam under conditions of slow, steady shear. The initial response of the foam is elastic. Above the yield strain, the foam begins to flow.
A. M. Kraynik +14 more
core +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Random neighbour model for yielding
We introduce a model for yielding, inspired by fracture models and the failure of a sheared granular medium in which the applied shear is resisted by self-organized force chains.
Dalton, Fergal +2 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Conformal Mapping on Rough Boundaries II: Applications to bi-harmonic problems
We use a conformal mapping method introduced in a companion paper to study the properties of bi-harmonic fields in the vicinity of rough boundaries. We focus our analysis on two different situations where such bi-harmonic problems are encountered: a ...
B. B. Mandelbrot +16 more
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

