Results 191 to 200 of about 3,599,226 (303)

Sensitivity of the stress field of the proximal femur predicted by CT-based FE analysis to modeling uncertainties. [PDF]

J Orthop Res, 2022
Youssefian S, Bressner JA, Osanov M, Guest JK, Zbijewski WB, Levin AS.   +5 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Investigation of the Strain-Stress Field in Nanoscale Multilayer Systems by the Phase Plane Method. [PDF]

Materials (Basel)
Belous D, Badalyan A, Khomenko A, Goncharov A.   +3 more
europepmc   +1 more source

Investigation of the Near-Tip Stress Field of a Notch Terminating at a Bi-Material Interface. [PDF]

Materials (Basel), 2021
Mieczkowski G, Szpica D, Borawski A, Awad MM, Elgarayhi A, Sallah M.   +5 more
europepmc   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Global residual stress field inference method for die-forging structural parts based on fusion of monitoring data and distribution prior. [PDF]

Vis Comput Ind Biomed Art
Chen S, Li Y, Liu C, Zhao Z, Chen Z, Liu X.   +5 more
europepmc   +1 more source

Analytical and Numerical Modeling of Stress Field and Fracture in Aluminum/Epoxy Interface Subjected to Laser Shock Wave: Application to Paint Stripping. [PDF]

Materials (Basel), 2022
Papadopoulos K, Tserpes K.
europepmc   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Monte Carlo Micro-Stress Field Simulations in Flax/E-Glass Composite Laminae with Non-Circular Flax Fibres. [PDF]

Polymers (Basel)
Yang N, Zou Z, Soutis C, Potluri P, Katnam KB.   +4 more
europepmc   +1 more source

Spatiotemporal Evolution of Stress Field during Direct Laser Deposition of Multilayer Thin Wall of Ti-6Al-4V. [PDF]

Materials (Basel), 2021
Ivanov S, Artinov A, Zemlyakov E, Karpov I, Rylov S, Em V.   +5 more
europepmc   +1 more source