Results 41 to 50 of about 519,341 (276)

Stress Map of Japan: Detailed Nationwide Crustal Stress Field Inferred From Focal Mechanism Solutions of Numerous Microearthquakes

Journal of Geophysical Research - Solid Earth, 2022
Crustal stress is a crucial parameter for understanding tectonics and assessing the occurrence of large earthquakes. Stress at seismogenic depths over a wide area has been inferred from focal mechanism solutions.
T. Uchide, T. Shiina, K. Imanishi
semanticscholar   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Study of in situ stress inversion of deeply incised valleys considering the river evolution process

Scientific Reports
The study of the in situ stress field is significant for the stability of large underground caverns near deep V-shaped valleys. Tectonic movements, gravity and river erosion have a great influence on the formation of the modern stress field.
Xianliang Wang, Changgui Zhao, Fenyuan Cheng, Zhiwei Ma, Wei Qi, Yinling Dou, Hao Lan, Jianhai Zhang, Benguo He, Lingying Peng, Wei Du   +10 more
doaj   +1 more source

Evolutionary sequence of faults and the formation of inversion structural belts in the northern Songliao Basin

Petroleum Exploration and Development, 2013
On the basis of regional seismic interpretation of the northern Songliao Basin and the analysis of fault geometry characteristics and the formation and evolution of faults, this paper analyses fault deformation mechanisms at different stages, which ...
Yonghe SUN, Yibo CHEN, Xuesong LI, Jigang SUN, Xiaofei FU   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

An Inverse Correlation between Corn Temperature and Nitrogen Stress: A Field Case Study [PDF]

Agronomy Journal, 2019
Nitrogen is one of the most important yield‐limiting nutrients for corn (Zea mays). The ability of thermal remote sensing to detect nitrogen deficiency in corn may enable precision agriculture to modify nitrogen rates according to field conditions.
Alzaben, Heba, Fraser, Roydon, Swanton, Clarence   +2 more
openaire   +2 more sources

Inversion and Analysis of the Initial Ground Stress Field of the Deep-Buried Tunnel Area

Applied Sciences, 2022
The detailed analysis of the initial ground stress distribution law is an important work for the safety of tunnel construction and operation. Especially, the high ground stress phenomenon in the deep-buried tunnel area is common, which has a great impact on the tunnel construction.
Rongsen Yu, Zhongsheng Tan, Junpeng Gao, Xiuying Wang, Jinpeng Zhao   +4 more
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source