Results 61 to 70 of about 359,894 (264)

Quantum fluctuations of fields and stress tensors

International Journal of Modern Physics A, 2022
This is a review of recent work on quantum fluctuations of the electric field and of stress tensor operators and their physical effects. The probability distribution for vacuum fluctuations of the electric field is Gaussian, but that for quadratic operators, such as the energy density, can have a more slowly decreasing tail, leading to an enhanced ...
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Algorithms of the Method of Statically Admissible Discontinuous Stress Fields (SADSF) – Part II: The Algorithms for Solving Limit Stress Fields Around Isolated Nodes of Stress Discontinuity Lines

Engineering Transactions, 2015
SUMMARY OF THE WHOLE PAPER: By now, the SADSF method is practically the only tool of shape design of complex machine elements that provides an effective solution even to the problems of 3D distribution of the material, and at the same time it is still ...
W. Bodaszewski
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Perception of risk from electric and magnetic fields: Stress effects and psychological aspects

Estudos de Psicologia (Campinas)
The present study aimed to investigate the perception of risk in the Brazilian population related to electric and magnetic fields. Six hundred adults were recruited from the surrounding communities.
Marilda Emmanuel Novaes Lipp, Flavio Eitor Barbieri, Leonel Santánna, Ana Paula Justo, Ana Carolina Cabral, Flavia Urbini dos Santos, Sabrina Gallo, Leeka Kheifets   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

SIMULATING MACHINING OF CONTINUOUSLY VARIABLE TRANSMISSION PULLEYS IN COMPLEX BLADE TOOL TRAJECTORY IN ANSYS SOFTWARE PACKAGE

Модели, системы, сети в экономике, технике, природе и обществе
Background. At the stage of developing the technological process of turning a part, it is important to identify the processes that occur as a result of the impact of the tool on the workpiece.
A.A. Generalova, A.A. Nikulin, D.S. Bychkov   +2 more
doaj   +1 more source

Potential flow of a second-order fluid over a tri-axial ellipsoid

Journal of Applied Mathematics, 2005
The problem of potential flow of a second-order fluid around an ellipsoid is solved, and the flow and stress fields are computed. The flow fields are determined by the harmonic potential but the stress fields depend on viscosity and the parameters of the
F. Viana, T. Funada, D. D. Joseph, N. Tashiro, Y. Sonoda   +4 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Representative volume elements of strain/stress fields measured by diffraction techniques. [PDF]

J Appl Crystallogr, 2023
Şeren MH, Pagan DC, Noyan IC.
europepmc   +1 more source