Results 111 to 120 of about 2,976,976 (292)

Animal models for investigating post‐stroke cognitive impairment: A neurovascular trafficking perspective

Animal Models and Experimental Medicine, EarlyView.
Animal models enable mechanistic testing of how ischemic injury disrupts neurovascular trafficking and drives cognitive vulnerability after stroke. Complementary models capture distinct vascular, cellular, white matter, and cognitive features of PSCI.
Pratchaya Kaewkaen
wiley   +1 more source

EFFECTS OF PRE-OPERATIVE ADMINISTRATION OF CONCENTRATED GLUCOSE IN ANASTHESIOLOGICAL SUPPORT DURING PULMONARY SURGERY

Вестник анестезиологии и реаниматологии, 2017
The article presents the experience of use and efficiency of pre-operative carbohydrate administration of 20% glucose intravenously during anasthesiological support of thorax cancer surgery.
V. A. Zhikharev, Yu. P. Malyshev, V. A. Porkhanov   +2 more
doaj   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Chitosan-based Moringa oleifera nanoparticles attenuate hyperglycemia-induced vascular endothelial growth factor upregulation in human lens epithelial cells

Journal of Advanced Pharmaceutical Technology & Research
Chronic hyperglycemia induces oxidative stress and stress-responsive signaling in ocular tissues, contributing to the progression of diabetic eye complications. Vascular endothelial growth factor (VEGF) is a key mediator of hyperglycemia-induced cellular
Hendra Susanto, Moch Sholeh, Nashi Widodo, Nurina Febriyanti Ayuningtyas, Miftakhul Cahyati, Adeodatus Yuda Handaya   +5 more
doaj   +1 more source

Stress hyperglycemia and electrolytes disturbance in patients with acute cerebrovascular stroke

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2019
Background Stroke is a medical emergency and considered the 2nd leading cause of mortality worldwide. High morbidity and mortality of stroke are due to some complications like cerebral edema, infection, and associated heart disease.
Bastawy M. El-Fawal, Reda Badry, Wael A. Abbas, Ahmed K. Ibrahim   +3 more
doaj   +1 more source

Hyperglycemia induces oxidative damage in SW872 cells [PDF]

, 2014
The high level of oxidative stress in obesity-­‐linked type 2 diabetes is associated with elevated formation of advanced glycation end products (AGEs).
Boyer, F, Bourdon, E, Rondeau, P
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

The Effects of Acute Hyperglycemia on Oxidant and Mechanical Stress

, 2000
Cardiovascular disease is a major cause of morbidity and mortality in diabetics. One complication of diabetes is hyperglycemia, whose acute effects include an increase in oxidant stress that results in an impaired endothelium-dependent vasodilatory ...
Gross, Eric R.
core  

Triglyceride Glucose Index and Stress Hyperglycemia are Important Factors for Predicting Early Neurological Deterioration in Isolated Acute Pontine Infarction

Brain and Behavior
Objective The triglyceride‐glucose (TyG) index and stress hyperglycemia (quantified as fasting plasma glucose/glycosylated hemoglobin ratio, GAR) are strongly associated with acute ischemic stroke (AIS) progression and adverse clinical outcomes. However,
Jian Ge, Chunjie Song, Yuanyuan Han
doaj   +1 more source

Economic evaluations of antiobesity medications: A systematic literature review

British Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković, Almir Fajkić, Andrea Katrin Faour, Mirna Momčilović, Petra Turčić, Andrej Belančić   +5 more
wiley   +1 more source