Results 131 to 140 of about 2,976,976 (292)

Beneficial Effects of Rosuvastatin and L-Arginine on High Glucose-Induced Oxidative Stress in Human Umbilical Vein Endothelial Cells

Cyprus Journal of Medical Sciences
BACKGROUND/AIMS: The study sought to examine the impact of rosuvastatin and L-arginine, alone or in combination, on hyperglycemia-caused oxidative stress in human umbilical vein endothelial cells (HUVECs). MATERIALS AND METHODS: HUVECs were divided into
Didem Yılmaz-Oral
doaj   +1 more source

Reactive Oxygen Species Modulate Coronary Wall Shear Stress and Endothelial Function During Hyperglycemia [PDF]

, 2003
Hyperglycemia is associated with generation of reactive oxygen species (ROS), and this action may contribute to accelerated atherogenesis. We tested the hypothesis that hyperglycemia produces alterations in left anterior descending coronary artery (LAD ...
LaDisa, John F., Weihrauch, Dorothee, Pagel, Paul S., Hettrick, Douglas Anthony, Olson, Lars E., Kersten, Judy R., Gross, Eric R., Warltier, David C., Kress, Tobias T.   +8 more
core  

Cognitive Behavioral Therapy for Binge‐Eating Disorder in Individuals With Type 2 Diabetes: A Pilot Randomized Controlled Trial

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To evaluate the feasibility of a randomized pilot trial of group‐based cognitive behavioral therapy (CBT) for binge eating disorder (BED) in individuals with type 2 diabetes, and to estimate exploratory clinical outcomes to inform the design of a future efficacy trial. Method Thirty‐four participants with type 2 diabetes and BED were
Pernille Fiil Nybo, Michael Einar Røder, Mia Beck Lichtenstein, René Klinkby Støving, Jakob Linnet   +4 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

A British Pharmacological Society Position Statement on Medications in Pregnancy and Lactation

British Journal of Clinical Pharmacology, EarlyView.
Agnesa Mustafa, Cleodie C. Swire, Reya V. Shah, Bernadette Jenner, Rory H. McLean, Muhammad Shamsher Ahmed, Adrie Bekker, Julia Zöllner, Rachel K. Scott, Robert R. Bies, Sara K. Quinney, Dagan O. Lonsdale, Emma Forton Magavern, Catriona Waitt, Anita Banerjee   +14 more
wiley   +1 more source

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

The association between stress hyperglycemia ratio and 1-year outcomes in patients with acute myocardial infarction: a retrospective large sample cohort study

Frontiers in Endocrinology
BackgroundThe Stress Hyperglycemia Ratio (SHR) is associated with poor outcomes in coronary artery disease patients, but its link to Acute Myocardial Infarction (AMI) prognosis is unclear.
Ning Yan, Peng Wu, Peng Wu, Zhengjun Zhang, Mohan Wang, Juan Ma, Ali Ma, Dapeng Chen, Xueping Ma, Xiaocheng Li   +9 more
doaj   +1 more source

Is Oxidative Stress a Consequence of Hyperglycemia? Or is Hyperglycemia the Consequence of Oxidative Stress? Or are Both Caused by Insulin Resistance? [PDF]

International Archives of Endocrinology Clinical Research, 2021
Boyacı İhsan, Yiğitbaşı Türkan, Ankaralı Handan   +2 more
openaire   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source