Results 181 to 190 of about 2,717,503 (245)
Parkinson's Disease and Retinal Age Gap: A Cross‐Sectional Analysis
Movement Disorders, EarlyView.Abstract Background Deep‐learning models are capable of predicting age from retinal scans and the difference between this and chronological age, retinal age gap, has been shown to be significantly associated with risk of mortality, cardiovascular diseases, and kidney failure.
Akshay Narayan +9 more
wiley +1 more source
Senotherapeutics for Knee Osteoarthritis
Medicinal Research Reviews, EarlyView.ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
National Materials, EarlyView.In this study, we engineered an antibacterial, antioxidative and epidermal grow factor‐encapsulated multifunctional hydrogel for the repair of chronic and refractory wounds. The hydrogel markedly promoted wound healing in rat models of diabetic foot ulcers and infected wounds by modulating wound microenvironment.
Zheng Zou +5 more
wiley +1 more source
Nutrition in Clinical Practice, EarlyView.Abstract Preoperative parenteral nutrition (PN) improves outcomes in malnourished surgical patients. Traditionally, this requires hospital admission, increasing length of stay and costs—challenges worsened by limited hospital bed availability. Outpatient PN may offer a feasible alternative.
Narisorn Lakananurak, Leah Gramlich
wiley +1 more source
Effect of GLP‐1 receptor agonist on nutrient intake: A narrative review
Nutrition in Clinical Practice, EarlyView.Abstract Humans have a primitive defense mechanism called metabolic adaptation that slows voluntary weight loss. It works by downregulating hormones that reduce food intake and by lowering the metabolic rate. Second‐generation GLP‐1 receptor agonists, such as semaglutide or tirzepatide, promote weight loss by targeting this hormonal system to control ...
Ken Fujioka
wiley +1 more source
Neuroprotection, EarlyView.Based on GBD 2021, the study analyzed the temporal trends of ischemic stroke (IS) burden in China from 1990 to 2021 and forecasted incidence and mortality through 2050. The absolute burden of IS in China will continue to rise by 2050, driven mainly by population aging, with faster age‐standardized incidence rate growth in females than males.
Yijun Zhang +5 more
wiley +1 more source
Obesity, EarlyView.ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter +14 more
wiley +1 more source
Obesity, EarlyView.ABSTRACT Objective BMI alone does not capture obesity‐related health heterogeneity. The Edmonton Obesity Staging System (EOSS) grades obesity severity based on comorbidities and functional impairment, whereas the Lancet Commission Diagnostic Model for Obesity (DMO) distinguishes preclinical from clinical obesity based on organ dysfunction.
Tobias Hagemann +3 more
wiley +1 more source
Bell's Palsy in 11,255 Cases: Cardiometabolic Associations in a Population‐Based Healthcare Database
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To estimate Bell's palsy incidence and evaluate the prevalence and associations with diabetes and other cardiometabolic conditions. Study Design Population‐based cohort study. Setting Clalit Health Services, the largest healthcare provider organization in Israel (2005‐2022).
Tomer Boldes +5 more
wiley +1 more source