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Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To evaluate the influence of patient comorbidities, social determinants of health (SDOH), and otolaryngology (OTO) referral timing on disease course and healthcare utilization among pediatric patients with recurrent croup. Study Design Retrospective cohort study. Setting Large tertiary children's hospital. Methods Pediatric patients (
Wesley P. Allen +8 more
wiley +1 more source
The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease
Pediatric Investigation, EarlyView.Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia +3 more
wiley +1 more source
Oxidative stress and hyperglycemia in aluminum phosphide poisoning.
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2014 Omid Mehrpour +2 more
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PLANTS, PEOPLE, PLANET, EarlyView.Medicinal plants used in ethnobotanical traditions to treat or prevent diseases have gained renewed interest for their largely untapped potential in drug discovery. In this study, we developed and tested novel methods to prioritise plant species based on their unexplored medicinal potential. By enabling researchers to target the most promising species,
Giovanni Zecca +3 more
wiley +1 more source
The Role of Stress Hyperglycemia on Delirium Onset
Journal of Clinical MedicineDelirium is an acute neuropsychiatric syndrome that recognizes one or more underlying causal medical conditions. Stress hyperglycemia usually refers to transient hyperglycemia associated with stress conditions such as stroke, myocardial infarction, and ...
Pasquale Mone +2 more
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Relative Hyperglycemia, a Marker of Critical Illness: Introducing the Stress Hyperglycemia Ratio [PDF]
Journal of Clinical Endocrinology and Metabolism, 2015 Hyperglycemia in hospitalized patients is associated with increased morbidity and mortality.We examined whether critical illness is more strongly associated with relative or absolute hyperglycemia.The study was an observational cohort study.A total of 2290 patients acutely admitted to a tertiary hospital.The relative hyperglycemia (stress hyperglycemia
Tariq Alhawassi +2 more
exaly +4 more sources
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Critical Care Clinics, 2001
Stress hyperglycemia is common and likely to be associated with at least some of the same complications as hyperglycemia in true diabetes mellitus, such as poor wound healing and a higher infection rate. The predominant cause is the intense counterregulatory hormone and cytokine responses of critical illness, often compounded by excessive dextrose ...
K C, McCowen, A, Malhotra, B R, Bistrian
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Stress hyperglycemia is common and likely to be associated with at least some of the same complications as hyperglycemia in true diabetes mellitus, such as poor wound healing and a higher infection rate. The predominant cause is the intense counterregulatory hormone and cytokine responses of critical illness, often compounded by excessive dextrose ...
K C, McCowen, A, Malhotra, B R, Bistrian
openaire +2 more sources
Does Hyperglycemia Cause Oxidative Stress in the Diabetic Rat Retina?
Cells, 2021 Diabetes, being a metabolic disease dysregulates a large number of metabolites and factors. However, among those altered metabolites, hyperglycemia is considered as the major factor to cause an increase in oxidative stress that initiates the ...
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Marked stress hyperglycemia in a child
Critical Care Medicine, 1982A 16-month-old child is presented who developed severe "stress hyperglycemia" with the onset of a respiratory distress syndrome. The serum glucose rose from 74 mg/dl to 520 mg/dl and returned to 52 mg/dl all within 24 h. These variations in serum glucose were paralleled by a similar marked increase in plasma cortisol concentration (from 41 to 90 to 36 ...
B, Chernow +4 more
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Stress Hyperglycemia, Inflammation, and Cardiovascular Events
Diabetes Care, 2003One-third of all individuals with hyperglycemia admitted to an urban general hospital do not have a previous diagnosis of diabetes; in these patients, hyperglycemia is a risk factor for adverse outcomes during acute illness (1). For example, in patients presenting with acute myocardial infarction, glucose values in excess of 6.1–8.0 mmol/l were ...
ESPOSITO, Katherine +2 more
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