Results 41 to 50 of about 2,717,503 (245)

Relationship between cytokine release and stress hyperglycemia in patients hospitalized with COVID-19 infection

Frontiers in Medicine, 2022
IntroductionStress hyperglycemia is a frequent finding in patients with COVID-19 infection and could affect the outcome of disease. Cytokines released in response to infection could have adverse effects on insulin sensitivity and pancreatic beta-cell ...
Andrea Da Porto, Carlo Tascini, Gianluca Colussi, Maddalena Peghin, Elena Graziano, Chiara De Carlo, Luca Bulfone, Martina Antonello, Emanuela Sozio, Martina Fabris, Francesco Curcio, Carlo Pucillo, Cristiana Catena, Leonardo A. Sechi   +13 more
doaj   +1 more source

Hyperglycemia in the Intensive Care Unit

, 2014
Hyperglycemia is frequently encountered in the intensive care unit. In this disease, after severe injury and during diabetes mellitus homeostasis is impaired; hyperglycemia, hypoglycemia and glycemic variability may ensue.
Ozan Akca, Rainer Lenhardt
core   +1 more source

Beneficial effects of the RESMENA Dietary pattern on oxidative stress in patients suffering from metabolic syndrome with hyperglycemia are associated to dietary TAC and fruit consumption [PDF]

, 2013
Hyperglycemia and oxidative stress are conditions directly related to the metabolic syndrome (MetS), whose prevalence is increasing worldwide. This study aimed to evaluate the effectiveness of a new weight-loss dietary pattern on improving the oxidative ...
Iglesia, R. (Rocío) de la, Martinez, J.A. (José Alfredo), Celada, P. (Paloma), Lopez-Legarrea, P. (Patricia), Sanchez-Muniz, F.J. (Francisco J.), J. Martinez, Patricia Lopez-legarrea, Paloma Celada, Rocio De La Iglesia, Francisco Sánchez-Muniz, De La Iglesia, Rocio, Celada, Paloma, Zulet, María Ángeles, Lopez Legarrea, Patricia, Martínez, J. Alfredo, M. Angeles Zulet, Sánchez Muniz, Francisco José, Zulet, M.A. (María Ángeles), J. Alfredo Martinez, Francisco J. Sánchez-muniz, M. Zulet   +20 more
core   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

The role of stress hyperglycemia in acute decompensated of heart failure

Сахарный диабет
BACKGROUND. The prevalence of chronic heart failure (CHF) and carbohydrate metabolism disorders (CMD) is steadily increasing in the 21st century.
O. A. Lozhkina, E. A. Schmidt, V. N. Karetnikova   +2 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Hypoxic stress in diabetic pregnancy contributes to impaired embryo gene expression and defective development by inducing oxidative stress

, 2005
We have shown that neural tube defects (NTD) in a mouse model of diabetic embryopathy are associated with deficient expression of Pax3, a gene required for neural tube closure. Hyperglycemia-induced oxidative stress is responsible.
Jung, Sung-Kwon, Chase, Martha, Li, Rulin, Smith, Peter J.S., Loeken, Mary R.   +4 more
core   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

Advanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn, Min‐seop Kim, Ju‐Hee Kim, Seok‐Hyeon Kang, Dain Lee, Hui‐Wen Liu, Seung‐cheol Shin, Kyuhwan Na, Yesl Jun, Oak‐Kee Hong, Ji Hun Yang, Jin‐A Kim, Hwanseok Jang, Hong Nam Kim, Roger D. Kamm, Ji‐Hoon Kim, Jang‐Won Son, Seok Chung   +17 more
wiley   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Stress hyperglycemia: An essential survival response!

, 2013
Stress hyperglycemia is common in critically ill patients and appears to be a marker of disease severity. Furthermore, both the admission as well as the mean glucose level during the hospital stay is strongly associated with patient outcomes. Clinicians,
Marik, PE, Bellomo, R
core   +1 more source