Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Numerical Calculation of Stress Intensity Factor of Tooth Root Crack in the High-speed EMU Gear
Jixie chuandong, 2017 In order to research the stress intensity factor of tooth root of the high-speed EMU gear,the location of crack initiation is determined by combining the finite element method and mapping method.
Li Xiuhong +4 more
doaj
Global Self-Esteem and Stress Intensity in a Group of Polish Nurses-A Mediatory Role of a Sense of Coherence. [PDF]
Int J Environ Res Public Health, 2022 Kupcewicz E.
europepmc +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
A Review on Reductions in the Stress-Intensity Factor of Cracked Plates Using Bonded Composite Patches. [PDF]
Materials (Basel), 2022 Aabid A, Hrairi M, Ali JSM, Sebaey TA.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Prediction Model of Stress Intensity Factor of Circumferential Through Crack in Elbow Based on Neural Network. [PDF]
Comput Intell Neurosci, 2022 Li X, Li X, Chen B.
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Influence of Stress Intensity Factor on Rail Fatigue Crack Propagation by Finite Element Method. [PDF]
Materials (Basel), 2021 Gao R, Liu M, Wang B, Wang Y, Shao W.
europepmc +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source