Results 111 to 120 of about 1,447,308 (304)

Mode I analysis of a cracked circular disk subject to a couple and a force [PDF]

open access: yes
Mode 1 stress intensity coefficients were obtained for an edge-cracked disk (round compact specimen). Results for this plane elastostatic problem, obtained by a boundary collocation analysis are presented for ratios 0.35 less than A/D less than 1, where ...
Gross, B.
core   +1 more source

Stress intensity factors of edge cracks in dissimilar joint plates [PDF]

open access: yes, 2014
Nowadays, there are many applications in which need the combination or different materials. The development of this is caused by the mechanical wear problem, a high temperature situation or other conditions in which different properties are required ...
Nik Ismail, Nik Ainun
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Stress analysis and stress intensity factors for finite geometry solids containing rectangular surface cracks [PDF]

open access: yes
The line method of analysis is applied to the Navier-Cauchy equations of elastic equilibrium to calculate the displacement field in a finite geometry bar containing a variable depth rectangular surface crack under extensionally applied uniform loading ...
Gyekenyesi, J. P., Mendelson, A.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Characterization of stress-strain state in gas turbine engine compressor disc taking into account damage accumulation

open access: yesFracture and Structural Integrity, 2019
The stress-strain state analysis of the gas turbine engine compressor disk was carried out taking into account damage accumulation under various loading conditions in the temperature range.
Natalia V Boychenko, Ivan Ishtyryakov
doaj  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Fracture parameters formulation for single edge notched AS4 stitched warp-knit fabric composite plate [PDF]

open access: yes, 2019
The three-dimensional problem of the fracture for the single edge notched tension plate (SENT) of orthotropic material is considered in this paper. The finite element solution is used to evaluate the singular and non-singular terms of the William series,
DJEBLI, Abdelkader   +2 more
core   +1 more source

Maximum Stress Intensity Factor for a Circumferential Crack in a Finite Length Cylinder under Transient Radial Temperature Distribution [PDF]

open access: yes
A method to evaluate the stress intensity factor of a circumferential crack in a finite length cylinder under non-linear radial temperature distribution, considering the effects of various structural parameters such as cylinder length and edge restraint,
渡邊, 勝彦, 飯井, 俊行
core  

Home - About - Disclaimer - Privacy