Mode I analysis of a cracked circular disk subject to a couple and a force [PDF]
Mode 1 stress intensity coefficients were obtained for an edge-cracked disk (round compact specimen). Results for this plane elastostatic problem, obtained by a boundary collocation analysis are presented for ratios 0.35 less than A/D less than 1, where ...
Gross, B.
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Stress intensity factors of edge cracks in dissimilar joint plates [PDF]
Nowadays, there are many applications in which need the combination or different materials. The development of this is caused by the mechanical wear problem, a high temperature situation or other conditions in which different properties are required ...
Nik Ismail, Nik Ainun
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Effect of Specimen Thickness and Stress Intensity Factor Range on Plasticity-Induced Fatigue Crack Closure in A7075-T6 Alloy. [PDF]
Masuda K, Ishihara S, Oguma N.
europepmc +1 more source
Stress analysis and stress intensity factors for finite geometry solids containing rectangular surface cracks [PDF]
The line method of analysis is applied to the Navier-Cauchy equations of elastic equilibrium to calculate the displacement field in a finite geometry bar containing a variable depth rectangular surface crack under extensionally applied uniform loading ...
Gyekenyesi, J. P., Mendelson, A.
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Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
The stress-strain state analysis of the gas turbine engine compressor disk was carried out taking into account damage accumulation under various loading conditions in the temperature range.
Natalia V Boychenko, Ivan Ishtyryakov
doaj
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Fracture parameters formulation for single edge notched AS4 stitched warp-knit fabric composite plate [PDF]
The three-dimensional problem of the fracture for the single edge notched tension plate (SENT) of orthotropic material is considered in this paper. The finite element solution is used to evaluate the singular and non-singular terms of the William series,
DJEBLI, Abdelkader +2 more
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Maximum Stress Intensity Factor for a Circumferential Crack in a Finite Length Cylinder under Transient Radial Temperature Distribution [PDF]
A method to evaluate the stress intensity factor of a circumferential crack in a finite length cylinder under non-linear radial temperature distribution, considering the effects of various structural parameters such as cylinder length and edge restraint,
渡邊, 勝彦, 飯井, 俊行
core

