Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal+2 more
wiley +1 more source
STRESS INTENSITY FACTORS FOR CIRCUMFERENTIAL PERIODIC CRACKED PIPES UNDER BENDING
Stress intensity factor is an important parameter that characterizes the stress field near the tip in fracture analysis. The simple and effective methods to estimate intensity factor become significant.
LIU WanJun, XIE YuJun
doaj
Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau+3 more
wiley +1 more source
Stress Intensity Factor of Circumferential Crack of Cylinders under Radial Temperature Distribution [PDF]
A simple equation to approximately calculate the stress intensity factor of the circumferential crack of cylinders under axisymmetric bending was derived first. By applying it, and equation to evaluate the stress intensity factor for the same crack under
渡邊, 勝彦, 飯井, 俊行
core
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
DIC2Abaqus: Calculating mixed-mode stress intensity factors from 2D and 3D-stereo displacement fields [PDF]
Integrating experimental data into simulations is crucial for predicting material behaviour, especially in fracture mechanics. Digital Image Correlation (DIC) provides precise displacement measurements, essential for evaluating strain energy release rates and stress intensity factors (SIF) around cracks.
arxiv
Stress intensity factors of edge cracks in dissimilar joint plates [PDF]
Nowadays, there are many applications in which need the combination or different materials. The development of this is caused by the mechanical wear problem, a high temperature situation or other conditions in which different properties are required ...
Nik Ismail, Nik Ainun
core
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Fatigue Life Appraisal and Its Corrected Stress Intensity Factor for Repaired Off-CentrallyCracked Aluminum Plates. [PDF]
You X+5 more
europepmc +1 more source
Maximum Stress Intensity Factor for a Circumferential Crack in a Finite Length Cylinder under Transient Radial Temperature Distribution [PDF]
A method to evaluate the stress intensity factor of a circumferential crack in a finite length cylinder under non-linear radial temperature distribution, considering the effects of various structural parameters such as cylinder length and edge restraint,
渡邊, 勝彦, 飯井, 俊行
core