Results 131 to 140 of about 915,307 (312)

Stress Distribution Around Roadway of Kunyang No. 2 Phosphate Mine: Analytical Study and Field Verification

Applied Sciences
When excavating roadways in underground mines, stress redistribution within the surrounding rock mass leads to stress concentration and release. Should the concentrated stresses exceed the rock mass’s tensile or shear strength, rock deformation and ...
Zongyong Wang, Kepeng Hou, Menglai Wang, Hao Wu   +3 more
doaj   +1 more source

Development and Evaluation of a Multifrequency Ultrafast Doppler Spectral Analysis (MFUDSA) Algorithm for Wall Shear Stress Measurement: A Simulation and In Vitro Study. [PDF]

Diagnostics (Basel), 2023
Malone AJ, Cournane S, Naydenova I, Meaney JF, Fagan AJ, Browne JE.   +5 more
europepmc   +1 more source

Self-report measures: an overview of concerns and limitations of questionnaire use in occupational stress research

, 2001
As is the case with many domains of organisational behaviour, occupational stress research has for many years been characterised by the use of self-report methodologies, in particular the written questionnaire, as the primary means of data collection ...
Razavi, Tiffani
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A Pipeline Hoop Stress Measurement Method Based on Propagation Path Correction of LCR Waves

Journal of Marine Science and Engineering
Pipelines are extensively used in offshore equipment. Accurate and non-destructive measurement of hoop stress conditions within pipes is critical for ensuring the integrity of offshore structures.
Bing Chen, Binbin Wang, Feifei Qiu, Chunlang Luo, Jiakai Chen, Guoqing Gou   +5 more
doaj   +1 more source

Stress Measurement in Primary Care: Conceptual Issues, Barriers, Resources, and Recommendations for Study. [PDF]

Psychosom Med, 2022
Wulsin LR, Sagui-Henson SJ, Roos LG, Wang D, Jenkins B, Cohen BE, Shah AJ, Slavich GM.   +7 more
europepmc   +1 more source

The roles of learning ability and stress reactivity in coping behaviour change: a CBT-based brief stress-management intervention

, 2012
CBT is well established as an effective treatment for a range of mental health problems and its use as a treatment for stress-related problems in occupational settings is also well evidenced; however, not every recipient of CBT necessarily shows ...
Scott, Josephine
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Association between Precarious Employment and Chronic Stress: Effect of Gender, Stress Measurement and Precariousness Dimensions-A Cross-Sectional Study. [PDF]

Int J Environ Res Public Health, 2022
Julià M, Méndez-Rivero F, Gómez-Gómez Á, Pozo ÓJ, Bolíbar M.   +4 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source