Results 121 to 130 of about 915,307 (312)

The nature, measurement and management of student nurse stress, distress and coping

, 2015
Following a review of the stress, distress and coping reported by student health professionals and students in higher education, see Chapters 2 and 3, the hypothesis that a problem existed with distress early in training was confirmed by screening two ...
Jones, Martyn C.
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

High precision and real-time acquisition system for interface stress measurement in bridge bearing. [PDF]

Sci Rep, 2023
Cao X, Li G, Li Z, Sun W, Yan F, Jiang R.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Residual Stress Measurement Techniques for Metal Joints, Metallic Coatings and Components in the Railway Industry: A Review. [PDF]

Materials (Basel), 2022
Kendall O, Paradowska A, Abrahams R, Reid M, Qiu C, Mutton P, Yan W.   +6 more
europepmc   +1 more source

“Integrated” digital image correlation for residual stress measurement

, 2013
Residual stress measuring by optical methods has been proposed by several authors in the past years; nevertheless the technique is still confined to optical laboratories: indeed the large sensitivity of the optical methods allows measuring very low ...
Filippo Bertolino, BERTOLINO, FILIPPO, Antonio Baldi, BALDI, ANTONIO   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Derivation of the stress concentrations at holes in orthotropic plates using thermoelastic stress analysis

, 2009
An experimental study of the stress distribution around holes in orthotropic composite laminates has been conducted using thermoelastic stress analysis (TSA).
Quinn, S., Sambasivam, S., Dulieu-Barton, J.M.   +2 more
core  

High performance laser survey and 3D stress analysis for maintenance and preservation of artistic assets

, 2020
The research described in this paper shows the results of preliminary analyses carried out on an artwork housed in a museum complex. A threedimensional model of the sculpture, resulting from a laser scanner survey, has been analysed to understand its ...
Marra A., Fabbrocino G., Gerbino S.
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source