Results 81 to 90 of about 384,475 (307)

Differential expression profile of DREB2 subfamily transcription factor genes in the dynamics of salt stress and post-stress recovery in tomato plants

Вавиловский журнал генетики и селекции
In response to stress, epigenetic modifications occur in the plant genome, which together form a stress memory that can be inherited and increases the efficiency of the plant's defense response to repeated stress events.
M. A. Filyushin, A. V. Shchennikova, E. Z. Kochieva   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Short-term prospective memory deficits in chronic back pain patients

, 2007
Objective: Chronic pain, particularly low back pain, is widespread. Although a great deal is known about the impact that this has on quality of life and physical activity, relatively little has been established regarding the more cognitive effects of ...
Heffernan, Tom, Greenough, Charles G., Ling, Jonathan, Campbell, Carol   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A torsion test for the study of the large deformation recovery of shape memory polymers [PDF]

, 2011
A torsion device was designed and built for testing the shape fixity and shape recovery of shape memory polymers at large deformation. A simple thermal chamber was used to regulate the thermal environment during testing and a CCD camera was used for ...
GILORMINI, Pierre, DIANI, Julie, FREDY, Carole, Carole Frédy, Pierre Gilormini, REGNIER, Gilles, Julie Diani, ROUSSEAU, Ingrid, Ingrid Rousseau, Yannick Merckel, Gilles Régnier, MERCKEL, Yannick   +11 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The effects of glucose dose and dual task performance on memory for emotional material. [PDF]

, 2010
Whilst previous research has shown that glucose administration can boost memory performance, research investigating the effects of glucose on memory for emotional material has produced mixed findings.
Brandt, Karen R., Sünram-Lea, Sandra I., Jenkinson, Paul M., Jones, Emma, Jenkinson, Paul, Brandt, K.R., Brandt, Karen R; id_orcid, Sünram-Lea, Sandra, Brandt, Karen, Sunram-Lea, S., Jenkinson, P., Jones, E.   +11 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Low lifetime stress exposure is associated with reduced stimulus–response memory

, 2017
Exposure to stress throughout life can cumulatively influence later health, even among young adults. The negative effects of high cumulative stress exposure are well-known, and a shift from episodic to stimulus–response memory has been proposed to ...
Elizabeth V. Goldfarb, Goldfarb, Elizabeth V., Shields, Grant S., Nathaniel D. Daw, Grant S. Shields, Elizabeth A. Phelps, Daw, Nathaniel D., George M. Slavich, Slavich, George M., Phelps, Elizabeth A.   +9 more
core   +1 more source

The effect of stress on the expression of the amyloid precursor protein in rat brain [PDF]

, 2008
The abnormal processing of the amyloid precursor protein (APP) is a pivotal event in the development of the unique pathology that defines Alzheimer's disease (AD).
Breen, Kieran C., Sayer, Rachel, Robertson, Deborah, Stewart, Caroline A., C. Breen, Kieran, J.K. Balfour, David, A. Stewart, Caroline, Balfour, David J.K., Balfour, David J. K.   +8 more
core   +1 more source