Results 121 to 130 of about 1,360,531 (316)

The SNF1-type serine-threonine protein kinase SAPK4 regulates stress-responsive gene expression in rice

, 2008
Diedhiou CJ, Popova OV, Dietz K-J, Golldack D. The SNF1-type serine-threonine protein kinase SAPK4 regulates stress-responsive gene expression in rice. BMC PLANT BIOLOGY.
Popova Olga V, Dietz, Karl-Josef, Diédhiou Calliste J, Golldack Dortje, Golldack, Dortje, Dietz Karl-Josef, Diedhiou, Calliste J., Popova, Olga V.   +7 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

The Stress Hyperglycemia Ratio is Associated with Hemorrhagic Transformation in Patients with Acute Ischemic Stroke

Clinical Interventions in Aging, 2021
Chengxiang Yuan,1,* Siyan Chen,1,* Yiting Ruan,1 Yuntao Liu,1 Haoran Cheng,1 Yaying Zeng,1 Yunbin Chen,1 Qianqian Cheng,2 Guiqian Huang,1 Weilei He,1 Jincai He1 1Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University ...
Yuan C, Chen S, Ruan Y, Liu Y, Cheng H, Zeng Y, Chen Y, Cheng Q, Huang G, He W, He J   +10 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The Nitric Oxide System in Peripheral Artery Disease: Connection with Oxidative Stress and Biopterins

, 2020
Peripheral artery disease (PAD) pathophysiology extends beyond hemodynamics to include other operating mechanisms, including endothelial dysfunction. Oxidative stress may be linked to endothelial dysfunction by reducing nitric oxide (NO) bioavailability.
Robert S. Smith, Jack Leigh Eidson, Luke P. Brewster, Jeffrey S. Kirk, Ramon Lavado, George P. Casale, Carlos Castro, William T. Bohannon, Iraklis I. Pipinos, Ahmed Ismaeel, Panagiotis Koutakis, Ian Sawicki, Evlampia Papoutsi, Robert Brumberg, Gleb Haynatzki, Aaron Hayson, Dimitrios Miserlis, Charalambos Konstantinou   +17 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Body Fat is Associated with Decreased Endocrine and Cognitive Resilience to Acute Emotional Stress

, 2008
*Objective:* Cortisol is elevated both in individuals with increased emotional stress as well as with higher percentages of body fat. Cortisol is also known to affect cognitive performance, particularly spatial processing, selective attention, and ...
Lilianne R. Mujica-Parodi, Rudolph Renelique, Marcus K. Taylor   +2 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The effect of stress ratio on functional behavior and structural fatigue of pseudoelastic niti alloy [PDF]

, 2019
The influence of stress ratio on functional behavior and structural fatigue of pseudoelastic NiTi alloy are studied. With the change of the stress ratio from 0 to 0.5 the residual strain in the first and next cycles increases significantly even at lower ...
Yasniy, P., Sobaszek, L., Lapusta, Y., Iasnii, V.   +3 more
core  

Fatigue Microcrack Initiation and Propagation of Aluminum Alloy under Different Stress Level and Stress Ratio

, 2011
The microstructure of fatigue fracture of aluminum alloys under various stresses and stress ratios were studied by optical microscope and scanning electron microscope, and the influences of microstructure features on microcrack initiation and propagation
Gui Xue Bian, Jian Jun Hu, Yue Liang Chen, Yong Zhang   +3 more
core   +1 more source