Results 131 to 140 of about 3,042,639 (351)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study [PDF]

, 2016
Catharina M. C. Mels, Hugo W. Huisman, Wayne Smith, Rudolph Schutte, Edzard Schwedhelm, Dorothee Atzler, Rainer H. Böger, Lisa J. Ware, Aletta E. Schutte   +8 more
openalex   +1 more source

Effects of stress ratio on plasticity-induced crack closure through three-dimensional advanced numerical finite element models

, 2023
Giovanna Calvín, Mikel Escalero, Haritz Zabala, Miguel Muñiz‐Calvente   +3 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Stress hyperglycemia ratio and physical frailty in HFpEF

Cardiovascular Diabetology
Background Stress hyperglycemia, reflected by the stress hyperglycemia ratio (SHR), is increasingly recognized as a marker of adverse cardiovascular outcomes in both diabetic and non-diabetic patients.
Pasquale Mone, Klara Komici, Germano Guerra, Tommaso Dazzetti, Urna Kansakar, Gianluca Gennarelli, Antonio Rainone, Gaetano Macina, Marco Di Mauro, Guido Iaccarino, Gianluca Testa, Gaetano Santulli   +11 more
doaj   +1 more source

A study of fatigue crack closure using electric potential and compliance techniques [PDF]

Compared are closure data produced on the same specimen by the crack tip compliance gage and electric potential techniques. Experiments on 7075-T651 aluminum center cracked panels produced equivalent results on closure using the two techniques.
Cassatt, G. C., Clarke, C. K.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Correlation between stress hyperglycemia ratio and risk of acute respiratory distress syndrome in patients with sepsis: a MIMIC-IV cohort study [PDF]

Xianwei Jin, Wei Deng, Qiaoling Weng, Fen Liu, Min Jia   +4 more
openalex   +1 more source

Effects of Zinc Supplementation on Plasma Copper/Zinc Ratios, Oxidative Stress, and Immunological Status in Hemodialysis Patients [PDF]

, 2013
Chih-Hung Guo, Chia‐Liang Wang
openalex   +1 more source

Assessment of exercise-induced stress via automated measurement of salivary cortisol concentrations and the testosterone-to-cortisol ratio [PDF]

, 2023
Katsuhiko Tsunekawa, Yoshifumi Shoho, Kazumi Ushiki, Yoshimaro Yanagawa, Ryutaro MATSUMOTO, Nozomi Shimoda, Tomoyuki Aoki, Akihiro Yoshida, Kiyomi Nakajima, Takao Kimura, Masami Murakami   +10 more
openalex   +1 more source