Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Effect of mindfulness stress reduction combined with cognitive behavioral therapy on perinatal anxiety disorder and maternal-infant bonding. [PDF]
Ge JD, Tang C, Shen Y.
europepmc +1 more source
Investigating perceived stress and pain reduction following brief Reiki sessions in high-stress communities: an exploratory study [PDF]
Heather McCutcheon, Sana Kausar Habiya
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Mindfulness-based stress reduction for sexual psychological recovery after radical cervical cancer surgery: A retrospective study. [PDF]
Sun QQ +5 more
europepmc +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Application of mindfulness-based stress reduction plan in post-stroke patients with mild depression. [PDF]
Pang X, Qiu D, He X, Xu J.
europepmc +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Pariya L Fazeli,1 David E Vance,1 Jeremy D Delgadillo,2 Shakaye R Haase,2 Crystal Chapman Lambert,1 Brittany L Bradley,1 Andres Azuero,1 Bulent Turan,3 Mirjam Colette Kempf1 1School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA ...
Fazeli PL +8 more
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