Results 101 to 110 of about 819,580 (307)
Probing microplasticity in small scale FCC crystals via Dynamic Mechanical Analysis [PDF]
, 2016 In small-scale metallic systems, collective dislocation activity has been correlated with size effects in strength and with a step-like plastic response under uniaxial compression and tension.
Adhikari, Rana X +4 more
core +5 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Aggregates relaxation in a jamming colloidal suspension after shear cessation
, 2005 The reversible aggregates formation in a shear thickening, concentrated colloidal suspension is investigated through speckle visibility spectroscopy, a dynamic light scattering technique recently introduced [P.K. Dixon and D.J. Durian, Phys. Rev.
B. J. Berne +6 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Majorana Fermions Under Uniaxial Stress in Semiconductor-Superconductor Heterostructures
, 2013 Spin-orbit coupled semiconductor nanowires with Zeeman splitting in proximity contact with bulk $s$-wave superconductivity have recently been proposed as a promising platform for realizing Majorana fermions.
Chuanwei Zhang +4 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Activated dynamics and effective temperature in a steady state sheared glass
, 2007 We conduct nonequilibrium molecular dynamics simulations to measure the shear stress, the average inherent structure energy, and the effective temperature $T_{eff}$ of a sheared model glass as a function of bath temperature $T$ and shear strain rate. For
Andrea J. Liu +3 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
StressesUnderstanding how thermal variability affects marine ectotherms is essential for predicting species resilience under climate change. We investigated the physiological responses of juvenile Nodipecten subnodosus (lion’s paw scallop), offspring of two ...
Natalia G. Joachin-Mejia +4 more
doaj +1 more source
Progress in Earth and Planetary Science, 2019 Combined knowledge on the magnitude as well as the orientation of paleo-stress is usually not given. Based on drilling investigations and laboratory experiments, we are able to provide both, constraints on paleo-stress magnitude as well as orientation in
Yoshitaka Hashimoto +3 more
doaj +1 more source