Results 51 to 60 of about 3,625,366 (264)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Thermally Induced Rock Stress Increment And Rock Reinforcement Response [PDF]

, 2016
The thermal heating caused by the deposition of spent nuclear fuel containers increases the in situ rock stress during disposal time. The thermal stress increase was modelled using thermo-mechanical modelling.
Hakala, Matti, Suikkanen, Johannes, Uotinen, Lauri, Nuijten, Guido, Siren, Topias, Ström, Jesse   +5 more
core   +1 more source

A Simplified FE Model of the Four-Ball Tester for Evaluating Stress and Strain Distributions [PDF]

INCAS Bulletin
This paper presents a simplified isothermal FE model of the four-ball tribotester in order to analyze stress and strain distributions, in mixt or boundary lubrication regime, for a range of loads and friction coefficients and the transition from a normal
Catalin PIRVU, Traian Florian IONESCU, Lorena DELEANU, Constantin GEORGESCU   +3 more
doaj   +1 more source

TRANSITION IN THE FRETTING PHENOMENON [PDF]

Fiabilitate şi Durabilitate, 2022
Fretting regimes were first mapped by Vingsbo. In a similar way, three fretting regimes will be considered: stick regime,slip regime and mixed regime.
Stefan GHIMISI
doaj  

Neotectonics and Geothermal potential of the East Anatolian Tectonic Block: A case study in Diyadin (Ağrı) geothermal field, NE Turkiye

Bulletin of the Mineral Research and Exploration, 2023
The study area is Diyadin, which is situated 71 km ESE of Ağrı very close to the Turkish-Iranian State border. It is one of several type localities of promising geothermal fields in the Eastern Anatolia.
Ali Koçyiğit
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Stressors, Appraisal of Stressors, Experienced Stress and Cardiac Response:A Real-Time, Real-Life Investigation of Work Stress in Nurses [PDF]

, 2015
Background: Stress in health care professionals may reflect both the work and appraisal of work and impacts on the individuals, their patients, colleagues and managers.Purpose: The purpose of the present study is to examine physiological and ...
Farquharson, B., Julia Allan, Marie Johnston, Martyn Jones (720171), Bell, Cheryl, Jones, Martyn C, Martyn Jones, Ian Ricketts (16669965), Marie Johnston (18271), Farquharson, Barbara, Derek Johnston, Johnston, D., Barbara Farquharson (16669962), Derek Johnston (3064002), Bell, C., Jones, M., Patricia Schofield, Jones, Martyn, Barbara Farquharson, Ricketts, I., Schofield, Patricia, Patricia Schofield (625809), Johnston, M., Cheryl Bell (16669959), Bell, Cheryl Louise, Cheryl Bell, Ian Ricketts, Johnston, Derek, Julia Allan (4991684), Allan, J., Allan, Julia, Johnston, Marie, Johnston, Derek W, Ricketts, Ian, Allan, Julia L   +34 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source