Results 71 to 80 of about 819,580 (307)

Complex Multi‐Fault Dynamics in Sikkim Himalaya: New Insights From Local Earthquake Analysis

Geochemistry, Geophysics, Geosystems
Anomalously overturned thrust faults, lineaments and segmentation causing cross‐cutting basement structures characterize the tectonic setting of Sikkim Himalaya.
Mita Uthaman, Chandrani Singh, Arun Singh, György Hetényi, Abhisek Dutta, Gaurav Kumar, Arun Kumar Dubey   +6 more
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Tri-critical behavior in rupture induced by disorder

, 1996
We discover a qualitatively new behavior for systems where the load transfer has limiting stress amplification as in real fiber composites. We find that the disorder is a relevant field leading to tri--criticality, separating a first-order regime where ...
A. A. Pollock, A. Aharony, A. G. Tumarkin, A. Hansen, A. N. Berker, A. Petri, A. Sornette, B. Voight, C. J. Allègre, C. Vanneste, D. Sornette, D. Sornette, D. Sornette, Didier Sornette, H. E. Daniels, I. G. Main, J. M. Normand, J. Schmittbuhl, J. V. Andersen, J.-C. Anifrani, Jørgen Vitting Andersen, K.-t. Leung, Kwan-tai Leung, L. Lamaignère, M. Berry, M. W. Suh, P. Diodati, P. K. Sen, R. F. Smalley, S. Alexander, S. J. Zhou, W. Newman   +31 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Stress Response in Confined Arrays of Frictional and Frictionless Particles [PDF]

, 2011
Stress transmission inside three dimensional granular packings is investigated using computer simulations. Localized force perturbation techniques are implemented for frictionless and frictional shallow, ordered, granular arrays confined by solid ...
Cakir, Abdullah, Silbert, Leonardo E.
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Effect of polymer-stress diffusion in the numerical simulation of elastic turbulence

, 2019
Elastic turbulence is a chaotic regime that emerges in polymer solutions at low Reynolds numbers. A common way to ensure stability in numerical simulations of polymer solutions is to add artificially large polymer-stress diffusion. In order to assess the
Gupta, Anupam, Vincenzi, Dario
core   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source