Results 111 to 120 of about 63,089 (309)

Study of microstructure and mechanical properties and residual stresses of 24CrNiMo steel prepared by selective laser melting and laser melting deposition

open access: yesJournal of Materials Research and Technology
Selective laser melting (SLM) and laser direct metal deposition (LMD) have shown promise in advanced manufacturing. However, limited research fabricating the same material using these methods, particularly regarding mechanical properties and residual ...
Yongsheng Zhao   +5 more
doaj   +1 more source

Early Stages of Fatigue Damage of Steels for Fusion Energetics [PDF]

open access: yes, 2012
Hlavním cílem této práce bylo vysvětlit únavové chování ocelí ODS Eurofer, 14Cr ODS feritické oceli vyráběné v CEA (Commissariat a l’énergie atomique, Saclay, France) a 14Cr ODS feritické oceli vyráběné v EPFL (École Polytechnique Fédérale de Laussane ...
Kuběna, Ivo
core  

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

open access: yesAdvanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu   +13 more
wiley   +1 more source

Application of Alloy 718 in M-1 engine components [PDF]

open access: yes
Alloy 718 applied to components of M-1 rocket ...
Frick, V.   +3 more
core   +1 more source

Powder metallurgical materials and processes for soft magnetic applications [PDF]

open access: yes, 2018
For many designers of electrical machines, the term “soft magnetic materials” automatically means laminated electrical sheet. This is unfortunate, since for many applications, particularly at low frequencies, laminated sheet is rarely the best material ...
Dougan, Mark J.
core  

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Growth of tin hillock and whisker under harmonic power conditions in tin-plated copper busbars for power system

open access: yesJournal of Materials Research and Technology
Tin hillock and whisker growth pose a serious reliability concern in tin-coated copper busbars, particularly in lead-free systems subjected to dynamic electrical environments. In this study, the influence of harmonic current stress on hillock and whisker
Tzu-Sen Su   +15 more
doaj   +1 more source

To Reduce the Fracture Mechanic at The Welding Spiral Pipe with Stress Relief Annealing [PDF]

open access: yes, 2011
Submerged Arc Welding (SAW) is welding process used for fabrication of pipes, for example spiral welded pipes. The technique can be operated automatically and has a high reliability in many various welding applications. Some Factor affecting the strength
Jufri, Mohammad   +2 more
core  

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu   +8 more
wiley   +1 more source

Investigation of residual stress influence on fatigue crack growth in remanufactured titanium alloy with inhomogeneous microstructure

open access: yesJournal of Materials Research and Technology
Laser remanufacturing technology is now the top choice for remanufacturing key components of aero-engines because of its cost-effectiveness, resource utilization, and performance recovery.
Xiaohong Zhan   +4 more
doaj   +1 more source

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